Nutraceuticals for Peripheral Vestibular Pathology: Properties, Usefulness, Future Perspectives and Medico-Legal Aspects.


Journal

Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595

Informations de publication

Date de publication:
18 Oct 2021
Historique:
received: 19 08 2021
revised: 09 10 2021
accepted: 13 10 2021
entrez: 23 10 2021
pubmed: 24 10 2021
medline: 20 11 2021
Statut: epublish

Résumé

Vestibular disorders may generate complex signs and symptoms, which may alter patients' balance and the quality of life. Dizziness and vertigo can strongly affect daily activities and relations. Despite the presence of conventional drugs, maneuvers, and surgery, another interesting therapeutic opportunity is offered by nutraceuticals. These molecules are often used in the treatment of dizziness and vertigo, but the rationale of their application is not always solidly demonstrated by the scientific evidence. Several substances have shown a variable level of efficacy/usefulness in this field, but there is lack of important evidence for most of them. From a medico-legal point of view, specific information must be provided to the patient regarding the efficacy and possibilities that the use of these preparations can allow. Administering the right nutraceutical to the proper patient is a fundamental clinical skill. Integrating conventional drug treatment with nutraceutical administration seems to be easy, but it may be difficult considering the (in part unexplored) pharmacodynamics and pharmacokinetics of nutraceuticals. The aim of the scientific community should be to elevate nutraceuticals to the same law and technical dignity of conventional drugs.

Identifiants

pubmed: 34684646
pii: nu13103646
doi: 10.3390/nu13103646
pmc: PMC8538675
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Giuseppe Chiarella (G)

Unit of Audiology, Department of Experimental and Clinical Medicine, Regional Centre of Cochlear Implants and ENT Diseases, Magna Graecia University, 88100 Catanzaro, Italy.

Gianmarco Marcianò (G)

Operative Unit of Pharmacology and Pharmacovigilance, "Mater Domini" Hospital, Department of Health Science, University Magna Graecia, 88100 Catanzaro, Italy.

Pasquale Viola (P)

Unit of Audiology, Department of Experimental and Clinical Medicine, Regional Centre of Cochlear Implants and ENT Diseases, Magna Graecia University, 88100 Catanzaro, Italy.

Caterina Palleria (C)

Operative Unit of Pharmacology and Pharmacovigilance, "Mater Domini" Hospital, Department of Health Science, University Magna Graecia, 88100 Catanzaro, Italy.

Davide Pisani (D)

Unit of Audiology, Department of Experimental and Clinical Medicine, Regional Centre of Cochlear Implants and ENT Diseases, Magna Graecia University, 88100 Catanzaro, Italy.

Vincenzo Rania (V)

Operative Unit of Pharmacology and Pharmacovigilance, "Mater Domini" Hospital, Department of Health Science, University Magna Graecia, 88100 Catanzaro, Italy.

Alessandro Casarella (A)

Operative Unit of Pharmacology and Pharmacovigilance, "Mater Domini" Hospital, Department of Health Science, University Magna Graecia, 88100 Catanzaro, Italy.

Alessia Astorina (A)

Unit of Audiology, Department of Experimental and Clinical Medicine, Regional Centre of Cochlear Implants and ENT Diseases, Magna Graecia University, 88100 Catanzaro, Italy.

Alfonso Scarpa (A)

Department of Medicine and Surgery, University of Salerno, 84081 Baronissi, Italy.

Massimiliano Esposito (M)

Department of Medical, Surgical and Advanced Technologies "G.F. Ingrassia", University of Catania, 95121 Catania, Italy.

Monica Salerno (M)

Department of Medical, Surgical and Advanced Technologies "G.F. Ingrassia", University of Catania, 95121 Catania, Italy.

Nunzio Di Nunno (N)

Department of History, Society and Studies on Humanity, University of Salento, 73100 Lecce, Italy.

Matteo Bolcato (M)

Legal Medicine, University of Padua, 35121 Padova, Italy.

Amalia Piscopo (A)

Forensic Medicine, Department of Law, Magna Graecia University of Catanzaro, 88100 Catanzaro, Italy.

Erika Cione (E)

Department of Pharmacy, Health and Nutritional Sciences, Department of Excellence 2018-2022, University of Calabria, 87036 Rende, Italy.

Giovambattista De Sarro (G)

Operative Unit of Pharmacology and Pharmacovigilance, "Mater Domini" Hospital, Department of Health Science, University Magna Graecia, 88100 Catanzaro, Italy.
Research Center FAS@UMG, Department of Health Science, University Magna Graecia, 88100 Catanzaro, Italy.

Giulio Di Mizio (G)

Forensic Medicine, Department of Law, Magna Graecia University of Catanzaro, 88100 Catanzaro, Italy.

Luca Gallelli (L)

Operative Unit of Pharmacology and Pharmacovigilance, "Mater Domini" Hospital, Department of Health Science, University Magna Graecia, 88100 Catanzaro, Italy.
Research Center FAS@UMG, Department of Health Science, University Magna Graecia, 88100 Catanzaro, Italy.

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