A Case of Mal De Meleda: The Rare Presentation of Palmoplantar Keratoderma Disease.
clinical dermatology
mal de meleda
palmoplantar keratoderma
rare diseases
scleroatrophic erythema
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
Sep 2021
Sep 2021
Historique:
accepted:
17
09
2021
entrez:
25
10
2021
pubmed:
26
10
2021
medline:
26
10
2021
Statut:
epublish
Résumé
Mal de Meleda (MDM) is a rare sub-type of palmoplantar keratoderma (PPK) disease. The primary symptoms of PPK are scleroatrophy, transient keratoderma, scleroatrophic erythema, pseudoainhum around the digits, and perioral erythema. MDM is a pathology with a difficult clinical course. This case study presents two cases of MDM in siblings born out of second-degree consanguinity. The presenting complaint was the peeling of the palmar skin since birth. Both patients were treated with acitretin orally (dose: 10 mg) for three months and tretinoin (topical) for two months. The prognosis was good after three months of treatment.
Identifiants
pubmed: 34692287
doi: 10.7759/cureus.18061
pmc: PMC8523366
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e18061Informations de copyright
Copyright © 2021, Kalyan et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
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