Synthesis, Computational Pharmacokinetics Report, Conceptual DFT-Based Calculations and Anti-Acetylcholinesterase Activity of Hydroxyapatite Nanoparticles Derived From

Alzheimer’s disease Conceptual DFT amyloid plaques computational pharmacokinetics molecular docking neurofibrillary tangles neuropathology

Journal

Frontiers in chemistry
ISSN: 2296-2646
Titre abrégé: Front Chem
Pays: Switzerland
ID NLM: 101627988

Informations de publication

Date de publication:
2021
Historique:
received: 15 07 2021
accepted: 17 09 2021
entrez: 25 10 2021
pubmed: 26 10 2021
medline: 26 10 2021
Statut: epublish

Résumé

Over the years, Alzheimer's disease (AD) treatments have been a major focus, culminating in the identification of promising therapeutic targets. A herbal therapy approach has been required by the demand of AD stage-dependent optimal settings. Present study describes the evaluation of anti-acetylcholinesterase (AChE) activity of hydroxyapatite nanoparticles derived from an

Identifiants

pubmed: 34692640
doi: 10.3389/fchem.2021.741037
pii: 741037
pmc: PMC8529163
doi:

Types de publication

Journal Article

Langues

eng

Pagination

741037

Informations de copyright

Copyright © 2021 Pradeep, Jain, Dharmashekara, Prasad, Akshatha, Pruthvish, Amachawadi, Srinivasa, Syed, Elgorban, Al Kheraif, Ortega-Castro, Frau, Flores-Holguín, Shivamallu, Kollur and Glossman-Mitnik.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Sushma Pradeep (S)

Department of Biotechnology and Bioinformatics, School of Life Sciences, JSS Academy of Higher Education and Research, Mysuru, India.

Anisha S Jain (AS)

Department of Biotechnology and Bioinformatics, School of Life Sciences, JSS Academy of Higher Education and Research, Mysuru, India.

Chandan Dharmashekara (C)

Department of Biotechnology and Bioinformatics, School of Life Sciences, JSS Academy of Higher Education and Research, Mysuru, India.

Shashanka K Prasad (SK)

Department of Biotechnology and Bioinformatics, School of Life Sciences, JSS Academy of Higher Education and Research, Mysuru, India.

Nagaraju Akshatha (N)

Department of Physics, Marimallapa PU College, Mysuru, India.

R Pruthvish (R)

Department of Biotechnology, Acharya Institute of Technology, Bengaluru, India.

Raghavendra G Amachawadi (RG)

Department of Clinical Sciences, College of Veterinary Medicine, Kansas State University, Manhattan, KS, United States.

Chandrashekar Srinivasa (C)

Department of Studies in Biotechnology, Davangere University, Shivagangothri, Davangere, India.

Asad Syed (A)

Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia.

Abdallah M Elgorban (AM)

Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia.

Abdulaziz A Al Kheraif (AA)

Dental Health Department, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.

Joaquín Ortega-Castro (J)

Departament de Química, Universitat de les Illes Balears, Palma de Mallorca, Spain.

Juan Frau (J)

Departament de Química, Universitat de les Illes Balears, Palma de Mallorca, Spain.

Norma Flores-Holguín (N)

Laboratorio Virtual NANOCOSMOS, Departamento de Medio Ambiente y Energía, Centro de Investigación en Materiales Avanzados, Chihuahua, México.

Chandan Shivamallu (C)

Department of Biotechnology and Bioinformatics, School of Life Sciences, JSS Academy of Higher Education and Research, Mysuru, India.

Shiva Prasad Kollur (SP)

Department of Sciences, Amrita School of Arts and Sciences, Amrita Vishwa Vidyapeetham, Mysuru Campus, Mysuru, India.

Daniel Glossman-Mitnik (D)

Laboratorio Virtual NANOCOSMOS, Departamento de Medio Ambiente y Energía, Centro de Investigación en Materiales Avanzados, Chihuahua, México.

Classifications MeSH