A Novel Endothelial Damage Inhibitor Reduces Oxidative Stress and Improves Cellular Integrity in Radial Artery Grafts for Coronary Artery Bypass.
bypass graft failure
coronary artery bypass grafting
endothelial damage inhibitor
oxidative damage
radial artery
Journal
Frontiers in cardiovascular medicine
ISSN: 2297-055X
Titre abrégé: Front Cardiovasc Med
Pays: Switzerland
ID NLM: 101653388
Informations de publication
Date de publication:
2021
2021
Historique:
received:
05
07
2021
accepted:
07
09
2021
entrez:
25
10
2021
pubmed:
26
10
2021
medline:
26
10
2021
Statut:
epublish
Résumé
The radial artery (RA) is a frequently used conduit in coronary artery bypass grafting (CABG). Endothelial injury incurred during graft harvesting promotes oxidative damage, which leads to graft disease and graft failure. We evaluated the protective effect of DuraGraft®, an endothelial damage inhibitor (EDI), on RA grafts. We further compared the protective effect of the EDI between RA grafts and saphenous vein grafts (SVG). Samples of RA (
Identifiants
pubmed: 34692789
doi: 10.3389/fcvm.2021.736503
pmc: PMC8527012
doi:
Types de publication
Journal Article
Langues
eng
Pagination
736503Informations de copyright
Copyright © 2021 Aschacher, Baranyi, Aschacher, Eichmair, Messner, Zimpfer, Moayedifar, Laufer, Emmert and Sandner.
Déclaration de conflit d'intérêts
SS is an investigator in the European VASC registry and a member of the registry scientific advisory committee. ME is the PI of the European VASC registry and the chair of the registry scientific advisory committee. Both have received consulting fees from Somahlution Inc, Jupiter, FL. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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