Mean Platelet Volume and Platelet Volume Distribution Width in Canine Parvoviral Enteritis.
gastrointestinal system (GIS)
mean platelet volume
parvoviral enteritis
platelet indices
platelet volume distribution width
Journal
Frontiers in veterinary science
ISSN: 2297-1769
Titre abrégé: Front Vet Sci
Pays: Switzerland
ID NLM: 101666658
Informations de publication
Date de publication:
2021
2021
Historique:
received:
08
06
2021
accepted:
13
09
2021
entrez:
25
10
2021
pubmed:
26
10
2021
medline:
26
10
2021
Statut:
epublish
Résumé
Bacterial translocation from the damaged intestinal tract, reported in canine parvoviral (CPV) enteritis, is thought to be responsible for the systemic inflammatory response resulting from coliform septicemia, which could ultimately progress to septic shock and death. Alterations in platelet indices, specifically mean platelet volume (MPV), is a consistent finding in critically ill people and dogs with and without sepsis. Increased MPV has been reported to be an indirect indicator of platelet activation and of bone marrow response in people and dogs with sepsis. The study aim was to compare admission MPV and platelet volume distribution width (PVDW) in dogs with CPV enteritis to that of healthy aged-matched control dogs. Forty-eight dogs with CPV enteritis and 18 healthy age matched control dogs were included. CPV infection was confirmed with electron microscopy and concurrent blood-borne infections were excluded using PCR. EDTA whole blood samples were analyzed on an automated cell counter, ADVIA 2120, within 30-60 min from collection. There was no significant difference for platelet count between the groups. The MPV for CPV infected dogs (median: 14.0;
Identifiants
pubmed: 34692806
doi: 10.3389/fvets.2021.722280
pmc: PMC8526561
doi:
Types de publication
Journal Article
Langues
eng
Pagination
722280Informations de copyright
Copyright © 2021 Engelbrecht, Atkinson, Goddard, Pazzi and McClure.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Biophys J. 1991 Apr;59(4):828-37
pubmed: 1905967
Intern Med. 2013;52(13):1487-93
pubmed: 23812196
J Clin Pathol. 1983 Jun;36(6):693-6
pubmed: 6343437
J Intensive Care. 2013 Dec 30;1(1):9
pubmed: 25810916
Cytometry. 1999 Oct 15;38(5):250-5
pubmed: 10516612
Br J Haematol. 1989 Jul;72(3):407-14
pubmed: 2765407
Res Vet Sci. 2011 Feb;90(1):89-94
pubmed: 20965082
J Am Vet Med Assoc. 2000 Nov 15;217(10):1500-4
pubmed: 11128540
J Am Vet Med Assoc. 2013 Aug 1;243(3):361-6
pubmed: 23865878
J Vet Intern Med. 2003 Sep-Oct;17(5):674-9
pubmed: 14529134
Hippokratia. 2010 Jan;14(1):28-32
pubmed: 20411056
Chest. 1993 Oct;104(4):1243-7
pubmed: 8404200
Am J Vet Res. 2005 Feb;66(2):325-9
pubmed: 15757135
Haematologica. 1998 Nov;83(11):1024-37
pubmed: 9864925
Minerva Anestesiol. 2006 Sep;72(9):749-56
pubmed: 16871155
Platelets. 2000 Nov;11(7):379-87
pubmed: 11132104
Vet Clin Pathol. 2008 Jun;37(2):159-63
pubmed: 18533914
Int J Infect Dis. 2010 Nov;14(11):e982-5
pubmed: 20851017
Mediators Inflamm. 2019 Apr 17;2019:9213074
pubmed: 31148950
Clin Infect Dis. 2000 Oct;31(4):851-8
pubmed: 11049761
Vet Clin Pathol. 2005 Jun;34(2):85-99
pubmed: 15902658
J Clin Invest. 2005 Dec;115(12):3339-47
pubmed: 16322778
Klin Wochenschr. 1989 Oct 17;67(20):1042-7
pubmed: 2586010
Intensive Care Med. 2004 Apr;30(4):536-55
pubmed: 14997291
Chest. 1999 May;115(5):1363-70
pubmed: 10334154
Oncologist. 1996;1(1 & 2):98-106
pubmed: 10387974
J Vet Intern Med. 1998 Sep-Oct;12(5):317-24
pubmed: 9773406
Blood. 1993 Jul 1;82(1):84-95
pubmed: 7686791
Stroke. 1995 Jun;26(6):995-9
pubmed: 7762052
J Small Anim Pract. 2008 Oct;49(10):518-24
pubmed: 18793252
Afr Health Sci. 2013 Jun;13(2):333-8
pubmed: 24235932
Mediterr J Hematol Infect Dis. 2013;5(1):e2013009
pubmed: 23350022
Nihon Juigaku Zasshi. 1989 Jun;51(3):597-606
pubmed: 2548025
J S Afr Vet Assoc. 2020 Jul 29;91(0):e1-e9
pubmed: 32787422
Int J Lab Hematol. 2008 Apr;30(2):117-23
pubmed: 18333843
Vet Clin Pathol. 1986;15(4):13-7
pubmed: 15334363
J Vet Intern Med. 1997 Mar-Apr;11(2):65-70
pubmed: 9127292
J Interferon Cytokine Res. 2000 May;20(5):499-506
pubmed: 10841078
Anaesth Intensive Care. 2007 Dec;35(6):874-80
pubmed: 18084977
Vet Clin North Am Small Anim Pract. 2010 Nov;40(6):1041-53
pubmed: 20933134
Blood. 2001 Nov 1;98(9):2720-5
pubmed: 11675343
Pancreatology. 2004;4(1):22-7
pubmed: 14988655
Blood. 1992 Jul 15;80(2):420-8
pubmed: 1627800
PLoS One. 2014 Aug 13;9(8):e103761
pubmed: 25118886
Thromb Haemost. 1979 May 25;41(3):491-7
pubmed: 462416
Immunol Today. 1994 Feb;15(2):74-80
pubmed: 7512342
Indian J Surg. 2015 Dec;77(Suppl 2):495-500
pubmed: 26730052
J Vet Emerg Crit Care (San Antonio). 2017 Sep;27(5):569-578
pubmed: 28749085
Vet Clin Pathol. 2015 Dec;44(4):493-7
pubmed: 26613563
Scand J Trauma Resusc Emerg Med. 2019 Feb 14;27(1):19
pubmed: 30764843