Identification and Quantitation of Neutrophil Extracellular Traps in Human Tissue Sections.

Confocal microscopy Lung NET quantitation Neutrophil Neutrophil extracellular traps Tissue sections

Journal

Bio-protocol
ISSN: 2331-8325
Titre abrégé: Bio Protoc
Pays: United States
ID NLM: 101635102

Informations de publication

Date de publication:
20 Sep 2021
Historique:
received: 23 12 2020
revised: 31 05 2021
accepted: 31 05 2021
entrez: 25 10 2021
pubmed: 26 10 2021
medline: 26 10 2021
Statut: epublish

Résumé

Neutrophils are one of the first innate immune cells recruited to tissues during inflammation. An important function of neutrophils relies on their ability to release extracellular structures, known as Neutrophil Extracellular Traps or NETs, into their environment. Detecting such NETs in humans has often proven challenging for both biological fluids and tissues; however, this can be achieved by quantitating NET components (

Identifiants

pubmed: 34692909
doi: 10.21769/BioProtoc.4159
pii: e4159
pmc: PMC8481026
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e4159

Informations de copyright

Copyright © 2021 The Authors; exclusive licensee Bio-protocol LLC.

Déclaration de conflit d'intérêts

Competing interestsThe authors declare no competing interests.

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Auteurs

Coraline Radermecker (C)

Laboratory of Immunophysiology, Grappe Interdisciplinaire de Genoproteomique Appliquee (GIGA) Institute, Liege University, Liege, Belgium.
Faculty of Veterinary Medicine, Liege University, Liege, Belgium.

Alexandre Hego (A)

Cell Imaging platform, Grappe Interdisciplinaire de Genoproteomique Appliquee (GIGA), Liege, Belgium.

Philippe Delvenne (P)

Department of Pathology, Clinique Hospitalo-Universitaire (CHU) University Hospital, Liege University, Liege, Belgium.
Laboratory of Experimental Pathology, Grappe Interdisciplinaire de Genoproteomique Appliquee (GIGA) Institute, Liege University, Liege, Belgium.

Thomas Marichal (T)

Laboratory of Immunophysiology, Grappe Interdisciplinaire de Genoproteomique Appliquee (GIGA) Institute, Liege University, Liege, Belgium.
Faculty of Veterinary Medicine, Liege University, Liege, Belgium.

Classifications MeSH