Non-alcoholic fatty liver disease: A patient guideline.
ALD, alcohol-related or alcoholic liver disease
ASH, alcoholic steatohepatitis
BMI, body mass index
CAP, controlled attenuation parameter
CT, computed tomography
CVD, cardiovascular disease
EASD, European Association for the Study of Diabetes
EASL, European Association for the Study of the Liver
EASO, European Association for the Study of Obesity
FIB-4, fibrosis-4 index
FXR, farnesoid X receptor
GLP-1 RAs, glucagon-like receptor 1 agonists
GP, general practitioner
HCC, hepatocellular carcinoma
HDL, high-density lipoprotein
LDL, low-density lipoproteins
MRE, magnetic resonance elastography
MRI, magnetic resonance imaging
NAFL, non-alcoholic fatty liver
NAFLD, non-alcoholic fatty liver disease
NASH CRN, NASH Clinical Research Network
NASH, non-alcoholic steatohepatitis
NIT, non-invasive test
SMART, specific, measurable, achievable, relevant, timely
T1D, type 1 diabetes
T2D, type 2 diabetes
Journal
JHEP reports : innovation in hepatology
ISSN: 2589-5559
Titre abrégé: JHEP Rep
Pays: Netherlands
ID NLM: 101761237
Informations de publication
Date de publication:
Oct 2021
Oct 2021
Historique:
received:
27
05
2021
accepted:
08
06
2021
entrez:
25
10
2021
pubmed:
26
10
2021
medline:
26
10
2021
Statut:
epublish
Résumé
This patient guideline is intended for all patients at risk of or living with non-alcoholic fatty liver disease (NAFLD). NAFLD is the most frequent chronic liver disease worldwide and comes with a high disease burden. Yet, there is a lot of unawareness. Furthermore, many aspects of the disease are still to be unravelled, which has an important impact on the information that is given (or not) to patients. Its management requires a close interaction between patients and their many healthcare providers. It is important for patients to develop a full understanding of NAFLD in order to enable them to take an active role in their disease management. This guide summarises the current knowledge relevant to NAFLD and its management. It has been developed by patients, patient representatives, clinicians and scientists and is based on current scientific recommendations, intended to support patients in making informed decisions.
Identifiants
pubmed: 34693236
doi: 10.1016/j.jhepr.2021.100322
pii: S2589-5559(21)00098-7
pmc: PMC8514420
doi:
Types de publication
Journal Article
Langues
eng
Pagination
100322Informations de copyright
© 2021 The Authors.
Déclaration de conflit d'intérêts
SMF has a senior clinical research mandate from the Fund for Scientific Research (FWO) Flanders (1802154 N) and has acted as advisor and/or lecturer for Roche, Gilead, Abbvie, Bayer, BMS, MSD, Janssen, Actelion, Astellas, Genfit, Inventiva, Intercept, Genentech, Galmed, Promethera, Coherus, NGM Bio and Julius Clinical. GM served as Advisory Board member for Sanofi, Novartis, Astra-Zeneca, Intercept and Pfizer, and participated in clinical trials by Sanofi, Eli Lilly, Gilead, GENFIT and Intercept. AK has received project grants from Novartis and Intercept. MW has nothing to disclose in relation to this publication. RD has received project grants from Novartis and Intercept. JVL received research grants from Gilead Sciences and MSD, and speaker fees from Genfit, Gilead Sciences, MSD, Intercept Pharmaceuticals and Janssen, outside of this work. SZS has nothing to disclose in relation to this publication. KH has nothing to disclose in relation to this publication. LB serves as an Advisory Board member for Novo Nordisk. GF has nothing to disclose in relation to this publication. DD served as Advisory Board member and lecture for Novo Nordisk, Sanofi, BI, Astra-Zeneca, and participated in clinical trials by, Novo Nordisk, Eli Lilly, Sanofi and BI. EW has nothing to disclose in relation to this publication. MK has nothing to disclose in relation to this publication. JW has nothing to disclose in relation to this publication. GK has nothing to disclose in relation to this publication. SV has nothing to disclose in relation to this publication. MU has nothing to disclose in relation to this publication. JM has nothing to disclose in relation to this publication. CL has nothing to disclose in relation to this publication. Please refer to the accompanying ICMJE disclosure forms for further details.
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