COVID-19 and the Incidence of Acute Myocardial Injury.


Journal

Hamostaseologie
ISSN: 2567-5761
Titre abrégé: Hamostaseologie
Pays: Germany
ID NLM: 8204531

Informations de publication

Date de publication:
Oct 2021
Historique:
entrez: 25 10 2021
pubmed: 26 10 2021
medline: 30 10 2021
Statut: ppublish

Résumé

Cardiovascular manifestations are frequent in COVID-19 infection and are predictive of adverse outcomes. Elevated cardiac biomarkers are common findings in patients with cardiovascular comorbidities and severe COVID-19 infection. Troponin, inflammatory and thrombotic markers may also improve risk prediction in COVID-19. In our comprehensive review, we provide an overview of the incidence, potential mechanisms and outcome of acute cardiac injury in COVID-19. Thereby, we discuss coagulation abnormalities in sepsis and altered immune response as contributing factors favoring myocardial injury. We further highlight the role of endothelial damage in the pathophysiological concepts. Finally, observational studies addressing the incidence of myocardial infarction during COVID-19 pandemic are discussed.

Identifiants

pubmed: 34695852
doi: 10.1055/a-1554-6416
doi:

Substances chimiques

Biomarkers 0
Troponin 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

356-364

Informations de copyright

Thieme. All rights reserved.

Déclaration de conflit d'intérêts

The authors declare that they have no conflict of interest.

Auteurs

Lars Mizera (L)

Department of Cardiology and Angiology, University of Tuebingen, Tuebingen, Germany.

Oliver Borst (O)

Department of Cardiology and Angiology, University of Tuebingen, Tuebingen, Germany.
DFG Heisenberg Group Thrombocardiology.

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Classifications MeSH