Brain MRI findings in COVID-19 patients with PRES: A systematic review.


Journal

Clinical imaging
ISSN: 1873-4499
Titre abrégé: Clin Imaging
Pays: United States
ID NLM: 8911831

Informations de publication

Date de publication:
Jan 2022
Historique:
received: 01 06 2021
revised: 21 09 2021
accepted: 05 10 2021
pubmed: 27 10 2021
medline: 24 11 2021
entrez: 26 10 2021
Statut: ppublish

Résumé

Numerous case reports and case series have described brain Magnetic Resonance Imaging (MRI) findings in Coronavirus disease 2019 (COVID-19) patients with concurrent posterior reversible encephalopathy syndrome (PRES). We aim to compile and analyze brain MRI findings in patients with COVID-19 disease and PRES. PubMed and Embase were searched on April 5th, 2021 using the terms "COVID-19", "PRES", "SARS-CoV-2" for peer-reviewed publications describing brain MRI findings in patients 21 years of age or older with evidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and PRES. Twenty manuscripts were included in the analysis, which included descriptions of 30 patients. The average age was 57 years old. Twenty-four patients (80%) required mechanical ventilation. On brain MRI examinations, 15 (50%) and 7 (23%) of patients exhibited superimposed foci of hemorrhage and restricted diffusion respectively. PRES is a potential neurological complication of COVID-19 related disease. COVID-19 patients with PRES may exhibit similar to mildly greater rates of superimposed hemorrhage compared to non-COVID-19 PRES patients.

Sections du résumé

BACKGROUND BACKGROUND
Numerous case reports and case series have described brain Magnetic Resonance Imaging (MRI) findings in Coronavirus disease 2019 (COVID-19) patients with concurrent posterior reversible encephalopathy syndrome (PRES).
PURPOSE OBJECTIVE
We aim to compile and analyze brain MRI findings in patients with COVID-19 disease and PRES.
METHODS METHODS
PubMed and Embase were searched on April 5th, 2021 using the terms "COVID-19", "PRES", "SARS-CoV-2" for peer-reviewed publications describing brain MRI findings in patients 21 years of age or older with evidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and PRES.
RESULTS RESULTS
Twenty manuscripts were included in the analysis, which included descriptions of 30 patients. The average age was 57 years old. Twenty-four patients (80%) required mechanical ventilation. On brain MRI examinations, 15 (50%) and 7 (23%) of patients exhibited superimposed foci of hemorrhage and restricted diffusion respectively.
CONCLUSIONS CONCLUSIONS
PRES is a potential neurological complication of COVID-19 related disease. COVID-19 patients with PRES may exhibit similar to mildly greater rates of superimposed hemorrhage compared to non-COVID-19 PRES patients.

Identifiants

pubmed: 34700172
pii: S0899-7071(21)00407-1
doi: 10.1016/j.clinimag.2021.10.003
pmc: PMC8519663
pii:
doi:

Types de publication

Journal Article Review Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

107-113

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

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Auteurs

Rubaya Yeahia (R)

New York Medical College, Valhalla, New York, United States of America.

Javin Schefflein (J)

Division of Neuroradiology, Department of Radiology, Westchester Medical Center, Valhalla, New York, United States of America.

Patrick Chiarolanzio (P)

Department of Radiology, New York Medical College, Valhalla, New York, United States of America.

Anna Rozenstein (A)

Division of Cardiothoracic Radiology, Department of Radiology, Westchester Medical Center, Valhalla, New York, United States of America.

William Gomes (W)

Division of Neuroradiology, Department of Radiology, Westchester Medical Center, Valhalla, New York, United States of America.

Sana Ali (S)

Division of Neuroradiology, Department of Radiology, Westchester Medical Center, Valhalla, New York, United States of America.

Hasit Mehta (H)

Division of Neuroradiology, Department of Radiology, Westchester Medical Center, Valhalla, New York, United States of America.

Fawaz Al-Mufti (F)

Department of Neurology, Westchester Medical Center, Valhalla, New York, United States of America.

Andrew McClelland (A)

Division of Neuroradiology, Department of Radiology, Montefiore Medical Center, Bronx, New York, United States of America.

Edwin Gulko (E)

Division of Neuroradiology, Department of Radiology, Westchester Medical Center, Valhalla, New York, United States of America. Electronic address: Edwin.Gulko@wmchealth.org.

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