Pseudomyxoma peritonei of appendiceal origin mimicking ovarian cancer - a case report with literature review.

appendectomy appendiceal neoplasm mucin ovarian tumors pseudomyxoma peritonei

Journal

Przeglad menopauzalny = Menopause review
ISSN: 1643-8876
Titre abrégé: Prz Menopauzalny
Pays: Poland
ID NLM: 101263235

Informations de publication

Date de publication:
Sep 2021
Historique:
received: 06 02 2021
accepted: 28 03 2021
entrez: 27 10 2021
pubmed: 28 10 2021
medline: 28 10 2021
Statut: ppublish

Résumé

Pseudomyxoma peritonei (PMP) is a rare and uncommon condition, characterized by the presence of mucinous ascites in the abdominal cavity. The most common cause of PMP is mucinous adenocarcinoma of the appendix, followed by neoplasms of the ovary, endocervix, fallopian tube, alimentary organs, urachus, urinary bladder, lung, mucinous cyst of the spleen, and breast. Herein, we report a case of a 64-year-old postmenopausal woman (gravida 2, para 2) who presented at the department of gynecology with a short history of nausea and abdominal distention. Abdominal and vaginal ultrasonography showed a large amount of free fluid in the pelvis with hyperechoic echogenicity and right pelvic tumor with mixed echogenicity. Computed tomography demonstrated the presence of a heterogeneous, hypodense mass, without contrast enhancement, located on the right side of the pelvis, near the right ovary. Laparotomy was performed. Revision of the abdominal cavity revealed a large amount of yellow gelatinous mucinous ascites - approximately 1.5 l. A tumor (6 x 7 cm in diameter), arising from the appendix and located in the pouch of Douglas near the right ovary, was observed. Histopathology examination revealed poorly differentiated mucinous appendiceal adenocarcinoma, comprising up to 50% signet ring cells. Gastrointestinal tumors such as appendiceal neoplasms combined with PMP may mimic ovarian carcinomas. Computed tomography, abdominal/vaginal ultrasonography and tumor marker levels (carcino-embryonic antigen, carbohydrate antigen 19.9, carbohydrate antigen Ca-125) may establish the diagnosis. A differential diagnosis with appendiceal tumors should be considered for patients with right pelvic masses.

Identifiants

pubmed: 34703416
doi: 10.5114/pm.2021.109120
pii: 45143
pmc: PMC8525259
doi:

Types de publication

Case Reports

Langues

eng

Pagination

148-153

Informations de copyright

Copyright © 2021 Termedia.

Déclaration de conflit d'intérêts

The authors report no conflict of interest.

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Auteurs

Stoyan Kostov (S)

Department of Gynecology, UMHAT "Saint Anna", Varna, Bulgaria.

Yavor Kornovski (Y)

Department of Gynecology, Medical University Varna "Prof. Dr. Paraskev Stoyanov", Varna, Bulgaria.

Stanislav Slavchev (S)

Department of Gynecology, Medical University Varna "Prof. Dr. Paraskev Stoyanov", Varna, Bulgaria.

Yonka Ivanova (Y)

Department of Gynecology, Medical University Varna "Prof. Dr. Paraskev Stoyanov", Varna, Bulgaria.

Deyan Dzhenkov (D)

Department of General and Clinical Pathology, Forensic Medicine and Deontology, Division of General and Clinical Pathology, Faculty of Medicine, Medical University Varna "Prof. Dr. Paraskev Stoyanov", Varna, Bulgaria.

Angel Yordanov (A)

Department of Gynecologic Oncology, Medical University Pleven, Pleven, Bulgaria.

Svetoslava Slavcheva (S)

Department of First Cardiology Clinic, UMHAT "Saint Anna", Varna, Bulgaria.

Classifications MeSH