Individual Differences in the Affective Response to Pandemic-Related Stressors in COVID-19 Health Care Workers.
Anxiety
COVID-19
Depression
Diagnostic heterogeneity
Stress
Journal
Biological psychiatry global open science
ISSN: 2667-1743
Titre abrégé: Biol Psychiatry Glob Open Sci
Pays: United States
ID NLM: 9918227369306676
Informations de publication
Date de publication:
Dec 2021
Dec 2021
Historique:
received:
21
04
2021
revised:
12
08
2021
accepted:
27
08
2021
pubmed:
28
10
2021
medline:
28
10
2021
entrez:
27
10
2021
Statut:
ppublish
Résumé
We investigated the evolving prevalence of mood and anxiety symptoms among health care workers from May 2020 to January 2021, risk factors for adverse outcomes, and characteristic modes of affective responses to pandemic-related stressors. A total of 2307 health care workers (78.9% female, modal age 25-34 years) participated in an online survey assessing depression (Patient Health Questionnaire-9) and anxiety (Generalized Anxiety Disorder-7 scale) symptoms, demographic variables, and self-reported impact of pandemic-related stressors. A total of 334 subjects were reassessed ∼6 months later. The prevalence of clinically significant depression and anxiety was 45.3% and 43.3%, respectively, and a majority (59.9%-62.9%) of those individuals had persistent significant symptoms at 6-month follow-up. Younger age, female gender, and specific occupations (support staff > nurses > physicians) were associated with increased depressive and anxiety symptoms. The most important risk factors were social isolation and fear of contracting COVID-19. The prevalence of clinically significant mood and anxiety symptoms increased by 39.8% from May 2020 to January 2021. Patient Health Questionnaire-9 and Generalized Anxiety Disorder-7 scores were highly correlated and associated with nearly identical risk factors, suggesting that they are not capturing independent constructs in this sample. Principal component analysis identified seven orthogonal symptom domains with unique risk factors. Clinically significant mood and anxiety symptoms are highly prevalent and persistent among health care workers, and are associated with numerous risk factors, the strongest of which are related to pandemic stressors and potentially modifiable. Interventions aimed at reducing social isolation and mitigating the impact of fear of infection warrant further study.
Sections du résumé
BACKGROUND
BACKGROUND
We investigated the evolving prevalence of mood and anxiety symptoms among health care workers from May 2020 to January 2021, risk factors for adverse outcomes, and characteristic modes of affective responses to pandemic-related stressors.
METHODS
METHODS
A total of 2307 health care workers (78.9% female, modal age 25-34 years) participated in an online survey assessing depression (Patient Health Questionnaire-9) and anxiety (Generalized Anxiety Disorder-7 scale) symptoms, demographic variables, and self-reported impact of pandemic-related stressors. A total of 334 subjects were reassessed ∼6 months later.
RESULTS
RESULTS
The prevalence of clinically significant depression and anxiety was 45.3% and 43.3%, respectively, and a majority (59.9%-62.9%) of those individuals had persistent significant symptoms at 6-month follow-up. Younger age, female gender, and specific occupations (support staff > nurses > physicians) were associated with increased depressive and anxiety symptoms. The most important risk factors were social isolation and fear of contracting COVID-19. The prevalence of clinically significant mood and anxiety symptoms increased by 39.8% from May 2020 to January 2021. Patient Health Questionnaire-9 and Generalized Anxiety Disorder-7 scores were highly correlated and associated with nearly identical risk factors, suggesting that they are not capturing independent constructs in this sample. Principal component analysis identified seven orthogonal symptom domains with unique risk factors.
CONCLUSIONS
CONCLUSIONS
Clinically significant mood and anxiety symptoms are highly prevalent and persistent among health care workers, and are associated with numerous risk factors, the strongest of which are related to pandemic stressors and potentially modifiable. Interventions aimed at reducing social isolation and mitigating the impact of fear of infection warrant further study.
Identifiants
pubmed: 34704087
doi: 10.1016/j.bpsgos.2021.08.008
pii: S2667-1743(21)00118-X
pmc: PMC8529885
doi:
Types de publication
Journal Article
Langues
eng
Pagination
336-344Subventions
Organisme : NIMH NIH HHS
ID : R01 MH118388
Pays : United States
Organisme : NIDA NIH HHS
ID : R01 DA047851
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH109685
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH123154
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH118451
Pays : United States
Informations de copyright
© 2021 The Authors.
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