6-Phosphogluconate dehydrogenase (6PGD), a key checkpoint in reprogramming of regulatory T cells metabolism and function.

Animals Mice Pentose Phosphate Pathway Phosphogluconate Dehydrogenase / genetics T-Lymphocytes, Regulatory / physiology
6PGD cell biology glucose immunoregulation metabolism mouse pentose phosphate pathway regulatory T cell

Journal

eLife
ISSN: 2050-084X
Titre abrégé: Elife
Pays: England
ID NLM: 101579614

Informations de publication

Date de publication:
28 10 2021
Historique:
received: 12 02 2021
accepted: 17 10 2021
entrez: 28 10 2021
pubmed: 29 10 2021
medline: 19 11 2021
Statut: epublish

Résumé

Cellular metabolism has key roles in T cells differentiation and function. CD4

Identifiants

DOI: 10.7554/eLife.67476 PMID: 34709178 PMC: PMC8553335
pubmed: 34709178
doi: 10.7554/eLife.67476
pii: 67476
pmc: PMC8553335
doi:
pii:

Substances chimiques

Phosphogluconate Dehydrogenase EC 1.1.1.43

Banques de données

SRA
['PRJNA706901']

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NCI NIH HHS
ID : P30 CA177558
Pays : United States
Organisme : NIDDK NIH HHS
ID : U24 DK097215
Pays : United States

Informations de copyright

© 2021, Daneshmandi et al.

Déclaration de conflit d'intérêts

SD, TC, RH, TF, PS No competing interests declared

Références

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Auteurs

Saeed Daneshmandi (S)

Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, United States.
Division of Interdisciplinary Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, United States.
ORCID: 0000-0001-7817-3006

Teresa Cassel (T)

Center for Environmental and Systems Biochemistry, University of Kentucky, Lexington, United States.
ORCID: 0000-0003-1700-932X

Richard M Higashi (RM)

Center for Environmental and Systems Biochemistry, University of Kentucky, Lexington, United States.

Teresa W-M Fan (TW)

Center for Environmental and Systems Biochemistry, University of Kentucky, Lexington, United States.
ORCID: 0000-0002-7292-8938

Pankaj Seth (P)

Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, United States.
Division of Interdisciplinary Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, United States.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › 6-Phosphogluconate dehydrogenase (6PGD), a key...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › 6-Phosphogluconate dehydrogenase (6PGD), a key...
questionsmedicales.fr › Métabolisme › Voies et réseaux métaboliques › Voie des pentoses phosphates › 6-Phosphogluconate dehydrogenase (6PGD), a key...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Oxidoreductases › Alcohol oxidoreductases › Carbohydrate dehydrogenases › Phosphogluconate dehydrogenase › 6-Phosphogluconate dehydrogenase (6PGD), a key...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Lymphocytes T › Sous-populations de lymphocytes T › Lymphocytes T régulateurs › 6-Phosphogluconate dehydrogenase (6PGD), a key...