Evaluation of different diagnostic modalities of minimal hepatic encephalopathy in cirrhotic patients: case-control study.
ammonia
critical flicker frequency
diagnosis
inhibitory control test
liver cirrhosis
minimal hepatic encephalopathy
overt
psychometric hepatic encephalopathy score
psychometric tests
serum 3-nitrotyrosine levels
Journal
Clinical and experimental hepatology
ISSN: 2392-1099
Titre abrégé: Clin Exp Hepatol
Pays: Poland
ID NLM: 101703431
Informations de publication
Date de publication:
Sep 2021
Sep 2021
Historique:
received:
24
02
2021
accepted:
13
06
2021
entrez:
29
10
2021
pubmed:
30
10
2021
medline:
30
10
2021
Statut:
ppublish
Résumé
Minimal hepatic encephalopathy (MHE) represents one of the most overlooked complications of liver cirrhosis. To compare the utility and efficacy of different MHE diagnostic modalities. This case-control study was conducted on hepatitis C virus (HCV)-related compensated cirrhotic patients. The Psychometric Hepatic Encephalopathy Score (PHES) was used to assign patients to MHE and controls. All patients were subjected to plasma ammonia, serum 3-nitrotyrosine (3-NT), critical flicker frequency (CFF), and the modified inhibitory control test (ICT). CFF was significantly lower in the control group (38.5, 40 Hz, 3-NT and ICT are advantageous to reveal MHE in compensated liver cirrhosis, while CFF can be only used as adjuncts, with humble merits of ammonia.
Identifiants
pubmed: 34712834
doi: 10.5114/ceh.2021.109292
pii: 45220
pmc: PMC8527340
doi:
Types de publication
Journal Article
Langues
eng
Pagination
312-319Informations de copyright
Copyright © 2021 Clinical and Experimental Hepatology.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
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