Peri-implantitis, systemic inflammation, and dyslipidemia: a cross-sectional biochemical study.
Cardiovascular diseases
Dyslipidemias
Inflammation
Leukocytes
Peri-implantitis
Journal
Journal of periodontal & implant science
ISSN: 2093-2278
Titre abrégé: J Periodontal Implant Sci
Pays: Korea (South)
ID NLM: 101526931
Informations de publication
Date de publication:
Oct 2021
Oct 2021
Historique:
received:
28
01
2021
revised:
30
03
2021
accepted:
29
04
2021
entrez:
29
10
2021
pubmed:
30
10
2021
medline:
30
10
2021
Statut:
ppublish
Résumé
The aim of this study was to compare the inflammatory and lipid profile of patients with and without peri-implantitis. A cross-sectional biochemical study was carried out in which blood samples were collected from 16 patients with peri-implantitis and from 31 subjects with healthy implants. Clinical peri-implant parameters were obtained from all subjects. Levels of tumor necrosis factor-alpha and interleukin-10 (IL-10) were measured in serum. Lipid fractions, glucose and creatinine levels, and complete blood count were also assessed. After controlling for a history of periodontitis, statistically significant differences between peri-implantitis patients and controls were found for total cholesterol (estimated adjusted mean difference, 76.4 mg/dL; 95% confidence interval [CI], 39.6, 113.2 mg/dL; Otherwise healthy individuals with peri-implantitis showed increased low-grade systemic inflammation and dyslipidemia.
Identifiants
pubmed: 34713995
pii: 51.342
doi: 10.5051/jpis.2100920046
pmc: PMC8558006
doi:
Types de publication
Journal Article
Langues
eng
Pagination
342-351Subventions
Organisme : Spanish Ministry of Economy and Competitiveness - Institute of Health Carlos III
Pays : Spain
Organisme : Osteology Foundation
ID : APB-MET-16-070
Pays : Spain
Organisme : Instituto de Investigación Sanitaria de Santiago de Compostela
Pays : Spain
Organisme : National Institute on Handicapped Research
ID : NIHR-INF-0387
Pays : Spain
Organisme : Instituto de Salud Carlos III
ID : CPII17/00027
Pays : Spain
Informations de copyright
Copyright © 2021. Korean Academy of Periodontology.
Déclaration de conflit d'intérêts
No potential conflict of interest relevant to this article was reported.
Références
J Periodontol. 1999 Dec;70(12):1429-34
pubmed: 10632517
PLoS One. 2011;6(5):e20240
pubmed: 21625524
J Clin Periodontol. 2011 Mar;38 Suppl 11:188-202
pubmed: 21323715
J Clin Periodontol. 2018 Jun;45 Suppl 20:S278-S285
pubmed: 29926496
J Periodontal Res. 2018 Oct;53(5):910-915
pubmed: 29961988
Circ Res. 2016 Feb 19;118(4):531-4
pubmed: 26892955
Nat Rev Immunol. 2015 Jan;15(1):30-44
pubmed: 25534621
J Dent Res. 2016 Jan;95(1):43-9
pubmed: 26701919
J Clin Epidemiol. 2008 Apr;61(4):344-9
pubmed: 18313558
J Clin Periodontol. 2018 Dec;45(12):1510-1520
pubmed: 30289569
Exp Hematol. 2021 Jan;93:1-13
pubmed: 33068648
Circ Res. 2016 Feb 19;118(4):732-49
pubmed: 26892970
Clin Oral Investig. 2020 Dec;24(12):4531-4539
pubmed: 32415398
Clin Implant Dent Relat Res. 2018 Apr;20(2):130-136
pubmed: 29148260
Atherosclerosis. 2018 Sep;276:98-108
pubmed: 30055326
J Periodontol. 2002 May;73(5):494-500
pubmed: 12027250
J Periodontol. 2018 Jun;89 Suppl 1:S267-S290
pubmed: 29926957
Clin Oral Implants Res. 2019 Apr;30(4):306-314
pubmed: 30768875
N Engl J Med. 1969 Nov 13;281(20):1081-6
pubmed: 5824173
J Periodontol. 2000 Aug;71(8):1375-84
pubmed: 10972656
Annu Rev Immunol. 2001;19:683-765
pubmed: 11244051
J Clin Periodontol. 2007 Nov;34(11):931-7
pubmed: 17877746
J Periodontol. 2021 Mar;92(3):436-445
pubmed: 32777099
J Lipid Res. 2004 Jul;45(7):1169-96
pubmed: 15102878
Clin Chem. 1986 Jan;32(1 Pt 1):142-5
pubmed: 3940695
Nat Rev Dis Primers. 2019 Aug 16;5(1):56
pubmed: 31420554
Arterioscler Thromb Vasc Biol. 2000 Jun;20(6):1536-42
pubmed: 10845869