Proposal of a new grading system for meningioma resection: the Copenhagen Protocol.
Meningioma
Neurooncology
Neuropathology
Neuroradiology
Neurosurgery
Journal
Acta neurochirurgica
ISSN: 0942-0940
Titre abrégé: Acta Neurochir (Wien)
Pays: Austria
ID NLM: 0151000
Informations de publication
Date de publication:
01 2022
01 2022
Historique:
received:
15
07
2021
accepted:
12
10
2021
pubmed:
30
10
2021
medline:
27
1
2022
entrez:
29
10
2021
Statut:
ppublish
Résumé
The extent of meningioma resection is the most fundamental risk factor for recurrence, and exact knowledge of extent of resection is necessary for prognostication and for planning of adjuvant treatment. Currently used classifications are the EANO-grading and the Simpson grading. The former comprises radiological imaging with contrast-enhanced MRI and differentiation between "gross total removal" and "subtotal removal," while the latter comprises a five-tiered differentiation of the surgeon's impression of the extent of resection. The extent of resection of tumors is usually defined via analyses of resection margins but has until now not been implemented for meningiomas. PET/MRI imaging with To develop an objective grading system based on microscopic analyses of resection margins and sensitive radiological analyses to improve management of follow-up, adjuvant therapy, and prognostication of meningiomas. Based on the rationale of resection-margin analyses as gold standard and superior imaging performance of Copenhagen Grading was described for six pilot patients with examples of positive and negative findings on histopathology and DOTATOC PET scanning. The grading could be traceably implemented and parameters of grading appeared complementary. Copenhagen Grading is prospectively implemented as a clinical standard at Rigshospitalet, Copenhagen. Copenhagen Grading provided a comprehensive, logical, and reproducible definition of the extent of resection. It offers promise to be the most sensitive and specific imaging modality available for meningiomas. Clinical and cost-efficacy remain to be established during prospective implementation.
Identifiants
pubmed: 34714434
doi: 10.1007/s00701-021-05025-5
pii: 10.1007/s00701-021-05025-5
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
229-238Commentaires et corrections
Type : CommentIn
Informations de copyright
© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature.
Références
Abry E, Thomassen IØ, Salvesen ØO, Torp SH (2010) The significance of Ki-67/MIB-1 labeling index in human meningiomas: a literature study. Pathol Res Pract 206(12):810–815
doi: 10.1016/j.prp.2010.09.002
Adegbite AB, Khan MI, Paine KW, Tan LK (1983) The recurrence of intracranial meningiomas after surgical treatment. J Neurosurg 58(1):51–56
doi: 10.3171/jns.1983.58.1.0051
Afshar-Oromieh A, Giesel FL, Linhart HG, Haberkorn U, Haufe S, Combs SE, Podlesek D, Eisenhut M, Kratochwil C (2012) Detection of cranial meningiomas: comparison of
doi: 10.1007/s00259-012-2155-3
Bashir A, Vestergaard MB, Binderup T, Broholm H, Marner L, Ziebell M, Fugleholm K, Mathiesen T, Kjær A, Law I (2020) Pharmacokinetic analysis of [(68)Ga]Ga-DOTA-TOC PET in meningiomas for assessment of in vivo somatostatin receptor subtype 2. Eur J Nucl Med Mol Imaging 47(11):2577–2588
doi: 10.1007/s00259-020-04759-1
Bashir A, Ziebell M, Fugleholm K, Law I (2015) A potential role of 68Ga-DOTATOC PET in modifying eligibility to surgery in patients with recurrent meningioma. J Nucl Med Radiat Ther. https://doi.org/10.4172/2155-9619.1000256
Bi WL, Greenwald NF, Abedalthagafi M et al (2017) Genomic landscape of high-grade meningiomas. NPJ genomic Med. https://doi.org/10.1038/s41525-017-0014-7
Birzu C, Peyre M, Sahm F (2020) Molecular alterations in meningioma: prognostic and therapeutic perspectives. Curr Opin Oncol 32(6):613–622
doi: 10.1097/CCO.0000000000000687
Borovich B, Doron Y (1986) Recurrence of intracranial meningiomas: the role played by regional multicentricity. J Neurosurg 64(1):58–63
doi: 10.3171/jns.1986.64.1.0058
Boulagnon-Rombi C, Fleury C, Fichel C, Lefour S, Marchal Bressenot A, Gauchotte G (2017) Immunohistochemical approach to the differential diagnosis of meningiomas and their mimics. J Neuropathol Exp Neurol 76(4):289–298
doi: 10.1093/jnen/nlx008
Brouwer de Koning SG, Vrancken Peeters M-JTFD, Jóźwiak K, Bhairosing PA, Ruers TJM (2018) Tumor resection margin definitions in breast-conserving surgery: systematic review and meta-analysis of the current literature. Clin Breast Cancer 18(4):e595–e600
doi: 10.1016/j.clbc.2018.04.004
Brouwer de Koning SG, Weijtmans P, Karakullukcu MB, Shan C, Baltussen EJM, Smit LA, van Veen RLP, Hendriks BHW, Sterenborg HJCM, Ruers TJM (2020) Toward assessment of resection margins using hyperspectral diffuse reflection imaging (400-1,700 nm) during tongue cancer surgery. Lasers Surg Med 52(6):496–502
doi: 10.1002/lsm.23161
Giamouriadis A, Perera D, Safdar A, Vergani F, Bhangoo R, Gullan R, Ashkan K (2019) Safety and accuracy of frameless electromagnetic-navigated (AXIEM(TM))-guided brain lesion biopsies: a large single-unit study. Acta Neurochir (Wien) 161(12):2587–2593
doi: 10.1007/s00701-019-04093-y
Goffredo P, Zhou P, Ginader T, Hrabe J, Gribovskaja-Rupp I, Kapadia M, You YN, Hassan I (2020) Positive circumferential resection margins following locally advanced colon cancer surgery: Risk factors and survival impact. J Surg Oncol 121(3):538–546
doi: 10.1002/jso.25801
Goldbrunner R, Minniti G, Preusser M et al (2016) EANO guidelines for the diagnosis and treatment of meningiomas. Lancet Oncol 17(9):e383–e391
doi: 10.1016/S1470-2045(16)30321-7
Hasseleid BF, Meling TR, Rønning P, Scheie D, Helseth E (2012) Surgery for convexity meningioma: Simpson Grade I resection as the goal: clinical article. J Neurosurg 117(6):999–1006
doi: 10.3171/2012.9.JNS12294
Jääskeläinen J (1986) Seemingly complete removal of histologically benign intracranial meningioma: late recurrence rate and factors predicting recurrence in 657 patients. A multivariate analysis. Surg Neurol 26(5):461–469
doi: 10.1016/0090-3019(86)90259-4
Jadid KD, Feychting M, Höijer J, Hylin S, Kihlström L, Mathiesen T (2015) Long-term follow-up of incidentally discovered meningiomas. Acta Neurochir (Wien) 157(2):225–230 discussion 230
doi: 10.1007/s00701-014-2306-3
Kleihues P, Louis DN, Scheithauer BW, Rorke LB, Reifenberger G, Burger PC, Cavenee WK (2002) The WHO classification of tumors of the nervous system. J Neuropathol Exp Neurol 61(3):215–225
doi: 10.1093/jnen/61.3.215
Lemée J-M, Corniola MV, Da Broi M, Joswig H, Scheie D, Schaller K, Helseth E, Meling TR (2019) Extent of resection in meningioma: predictive factors and clinical implications. Sci Rep 9(1):5944
doi: 10.1038/s41598-019-42451-z
Lemée J-M, Corniola MV, Meling TR (2020) Benefits of re-do surgery for recurrent intracranial meningiomas. Sci Rep 10(1):303
doi: 10.1038/s41598-019-57254-5
Louis DN, Perry A, Reifenberger G, von Deimling A, Figarella-Branger D, Cavenee WK, Ohgaki H, Wiestler OD, Kleihues P, Ellison DW (2016) The 2016 world health organization classification of tumors of the central nervous system: a summary. Acta Neuropathol 131(6):803–820
doi: 10.1007/s00401-016-1545-1
Lu Y, Yeung C, Radmanesh A, Wiemann R, Black PM, Golby AJ (2015) Comparative effectiveness of frame-based, frameless, and intraoperative magnetic resonance imaging-guided brain biopsy techniques. World Neurosurg 83(3):261–268
doi: 10.1016/j.wneu.2014.07.043
Maier AD, Stenman A, Svahn F, Mirian C, Bartek JJ, Juhler M, Zedenius J, Broholm H, Mathiesen T (2021) TERT promoter mutations in primary and secondary WHO grade III meningioma. Brain Pathol 31(1):61–69
doi: 10.1111/bpa.12892
Mathiesen T, Lindquist C, Kihlström L, Karlsson B (1996) Recurrence of cranial base meningiomas. Neurosurgery 39(1):2–9
doi: 10.1097/00006123-199607000-00002
Mathiesen T, Pettersson-Segerlind J, Kihlström L, Ulfarsson E (2014) Meningiomas engaging major venous sinuses. World Neurosurg 81(1):116–124
doi: 10.1016/j.wneu.2013.01.095
Meling TR, Da Broi M, Scheie D, Helseth E (2019) Meningiomas: skull base versus non-skull base. Neurosurg Rev 42(1):163–173
doi: 10.1007/s10143-018-0976-7
Milker-Zabel S, Zabel-du Bois A, Henze M, Huber P, Schulz-Ertner D, Hoess A, Haberkorn U, Debus J (2006) Improved target volume definition for fractionated stereotactic radiotherapy in patients with intracranial meningiomas by correlation of CT, MRI, and [68Ga]-DOTATOC-PET. Int J Radiat Oncol Biol Phys 65(1):222–227
doi: 10.1016/j.ijrobp.2005.12.006
Mirian C, Duun-Henriksen AK, Juratli T et al (2020) Poor prognosis associated with TERT gene alterations in meningioma is independent of the WHO classification: an individual patient data meta-analysis. J Neurol Neurosurg Psychiatry 91(4):378–387
doi: 10.1136/jnnp-2019-322257
Mirian C, Skyrman S, Bartek JJ, Jensen LR, Kihlström L, Förander P, Orrego A, Mathiesen T (2020) The Ki-67 proliferation index as a marker of time to recurrence in intracranial meningioma. Neurosurgery. https://doi.org/10.1093/neuros/nyaa226
Mirimanoff RO, Dosoretz DE, Linggood RM, Ojemann RG, Martuza RL (1985) Meningioma: analysis of recurrence and progression following neurosurgical resection. J Neurosurg 62(1):18–24
doi: 10.3171/jns.1985.62.1.0018
Ostrom QT, Cioffi G, Gittleman H, Patil N, Waite K, Kruchko C, Barnholtz-Sloan JS (2019) CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2012-2016. Neuro Oncol 21(Suppl 5):v1–v100
doi: 10.1093/neuonc/noz150
Patel AJ, Wan Y-W, Al-Ouran R et al (2019) Molecular profiling predicts meningioma recurrence and reveals loss of DREAM complex repression in aggressive tumors. Proc Natl Acad Sci U S A 116(43):21715–21726
doi: 10.1073/pnas.1912858116
Pettersson-Segerlind J, Orrego A, Lönn S, Mathiesen T (2011) Long-term 25-year follow-up of surgically treated parasagittal meningiomas. World Neurosurg 76(6):564–571
doi: 10.1016/j.wneu.2011.05.015
Rogers L, Barani I, Chamberlain M, Kaley TJ, McDermott M, Raizer J, Schiff D, Weber DC, Wen PY, Vogelbaum MA (2015) Meningiomas: knowledge base, treatment outcomes, and uncertainties. A RANO review. J Neurosurg 122(1):4–23
doi: 10.3171/2014.7.JNS131644
Roggendorf W, Schuster T, Peiffer J (1987) Proliferative potential of meningiomas determined with the monoclonal antibody Ki-67. Acta Neuropathol 73(4):361–364
doi: 10.1007/BF00688260
Sahm F, Schrimpf D, Stichel D et al (2017) DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis. Lancet Oncol 18(5):682–694
doi: 10.1016/S1470-2045(17)30155-9
Schwartz TH, McDermott MW (2020) The Simpson grade: abandon the scale but preserve the message. J Neurosurg:1–8
Sievers P, Hielscher T, Schrimpf D et al (2020) CDKN2A/B homozygous deletion is associated with early recurrence in meningiomas. Acta Neuropathol 140(3):409–413
doi: 10.1007/s00401-020-02188-w
Simpson D (1957) The recurrence of intracranial meningiomas after surgical treatment. J Neurol Neurosurg Psychiatry 20(1):22–39
doi: 10.1136/jnnp.20.1.22
Slot KM, Verbaan D, Bosscher L, Sanchez E, Vandertop WP, Peerdeman SM (2018) Agreement between extent of meningioma resection based on surgical simpson grade and based on postoperative magnetic resonance imaging findings. World Neurosurg 111:e856–e862
doi: 10.1016/j.wneu.2017.12.178
Suppiah S, Nassiri F, Bi WL et al (2019) Molecular and translational advances in meningiomas. Neuro Oncol 21(Suppl 1):i4–i17
doi: 10.1093/neuonc/noy178
Williams EA, Santagata S, Wakimoto H et al (2020) Distinct genomic subclasses of high-grade/progressive meningiomas: NF2-associated, NF2-exclusive, and NF2-agnostic. Acta Neuropathol Commun 8(1):171
doi: 10.1186/s40478-020-01040-2
Youngblood MW, Duran D, Montejo JD et al (2019) Correlations between genomic subgroup and clinical features in a cohort of more than 3000 meningiomas. J Neurosurg:1–10