γδ T Cells Differentially Regulate Bone Loss in Periodontitis Models.

Alveolar Bone Loss Animals Bone Diseases, Metabolic Disease Models, Animal Mice Mice, Inbred C57BL Periodontitis / pathology Porphyromonas gingivalis T-Lymphocytes
Porphyromonas gingivalis innate immunity ligature oral mucosa osteoclasts periodontitis

Journal

Journal of dental research
ISSN: 1544-0591
Titre abrégé: J Dent Res
Pays: United States
ID NLM: 0354343

Informations de publication

Date de publication:
04 2022
Historique:
pubmed: 31 10 2021
medline: 16 4 2022
entrez: 30 10 2021
Statut: ppublish

Résumé

γδ T cells are nonclassical T lymphocytes representing the major T-cell population at epithelial barriers. In the gingiva, γδ T cells are enriched in epithelial regions adjacent to the biofilm and are considered to regulate local immunity to maintain host-biofilm homeostatic interactions. This delicate balance is often disrupted resulting in the development of periodontitis. Previous studies in mice lacking γδ T cells from birth (

Identifiants

DOI: 10.1177/00220345211042830 PMID: 34715745
pubmed: 34715745
doi: 10.1177/00220345211042830
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

428-436

Auteurs

O Barel (O)

Institute of Biomedical and Oral Research, Hebrew University, Jerusalem, Israel.

Y Aizenbud (Y)

Institute of Biomedical and Oral Research, Hebrew University, Jerusalem, Israel.

Y Tabib (Y)

Institute of Biomedical and Oral Research, Hebrew University, Jerusalem, Israel.

Y Jaber (Y)

Institute of Biomedical and Oral Research, Hebrew University, Jerusalem, Israel.

A Leibovich (A)

Institute of Biomedical and Oral Research, Hebrew University, Jerusalem, Israel.

Y Horev (Y)

Institute of Biomedical and Oral Research, Hebrew University, Jerusalem, Israel.
Department of Periodontology, Faculty of Dental Medicine, Hebrew University, Jerusalem, Israel.

K Zubeidat (K)

Institute of Biomedical and Oral Research, Hebrew University, Jerusalem, Israel.

Y Saba (Y)

Institute of Biomedical and Oral Research, Hebrew University, Jerusalem, Israel.

L Eli-Berchoer (L)

Institute of Biomedical and Oral Research, Hebrew University, Jerusalem, Israel.

O Heyman (O)

Institute of Biomedical and Oral Research, Hebrew University, Jerusalem, Israel.
Department of Periodontology, Faculty of Dental Medicine, Hebrew University, Jerusalem, Israel.

A Wilensky (A)

Department of Periodontology, Faculty of Dental Medicine, Hebrew University, Jerusalem, Israel.

I Prinz (I)

Institute of Immunology, Hannover Medical School, Hannover, Germany.
Institute of Systems Immunology, Hamburg Center for Translational Immunology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
ORCID: 0000-0002-8789-9578

A H Hovav (AH)

Institute of Biomedical and Oral Research, Hebrew University, Jerusalem, Israel.

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Classifications MeSH

questionsmedicales.fr › Maladies du système stomatognathique › Maladies de la bouche › Maladies parodontales › Atrophie parodontale › Résorption alvéolaire › γδ T Cells Differentially Regulate Bone Loss...
questionsmedicales.fr › Eucaryotes › Animaux › γδ T Cells Differentially Regulate Bone Loss...
questionsmedicales.fr › Maladies métaboliques et nutritionnelles › Maladies métaboliques › Maladies osseuses métaboliques › γδ T Cells Differentially Regulate Bone Loss...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles biologiques › Modèles animaux de maladie humaine › γδ T Cells Differentially Regulate Bone Loss...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › γδ T Cells Differentially Regulate Bone Loss...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée C57BL › γδ T Cells Differentially Regulate Bone Loss...
questionsmedicales.fr › Maladies du système stomatognathique › Maladies de la bouche › Maladies parodontales › Parodontite › γδ T Cells Differentially Regulate Bone Loss...
questionsmedicales.fr › Bactéries › Bactéries à Gram négatif › Bactéries anaérobies à Gram négatif › Bâtonnets à Gram négatif anaérobies droits, incurvés et spiralés › Bacteroidaceae › Porphyromonas › Porphyromonas gingivalis › γδ T Cells Differentially Regulate Bone Loss...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Lymphocytes T › γδ T Cells Differentially Regulate Bone Loss...