Scleroderma and the Esophagus.
Aperistalsis
Dysphagia
Ehler-Danlos
Fibromyalgia
Lupus
Myositis
Scleroderma
Sjogren
Journal
Gastroenterology clinics of North America
ISSN: 1558-1942
Titre abrégé: Gastroenterol Clin North Am
Pays: United States
ID NLM: 8706257
Informations de publication
Date de publication:
12 2021
12 2021
Historique:
entrez:
31
10
2021
pubmed:
1
11
2021
medline:
28
1
2022
Statut:
ppublish
Résumé
The gastrointestinal tract is the second largest organ system in the body and is often affected by connective tissue disorders. Scleroderma is the classic rheumatologic disease affecting the esophagus; more than 90% of patients with scleroderma have esophageal involvement. This article highlights esophageal manifestations of scleroderma, focusing on pathogenesis, clinical presentation, diagnostic considerations, and treatment options. In addition, this article briefly reviews the esophageal manifestations of other key connective tissue disorders, including mixed connective tissue disease, myositis, Sjogren syndrome, systemic lupus erythematosus, fibromyalgia, and Ehlers-Danlos syndrome.
Identifiants
pubmed: 34717878
pii: S0889-8553(21)00709-3
doi: 10.1016/j.gtc.2021.08.005
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
905-918Informations de copyright
Copyright © 2021 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Disclosure J.O. Clarke has received honoraria for consulting from Alnylam, Isothrive, Medtronic, Regeneron, and Sanofi. N.K. Ahuja has served on advisory boards for Takeda and Laborie and has received honoraria for consulting from Medtronic and GlaxoSmithKline and research support from Nestle and Vanda. No conflicts of interest exist.