Relationships between social withdrawal and facial emotion recognition in neuropsychiatric disorders.


Journal

Progress in neuro-psychopharmacology & biological psychiatry
ISSN: 1878-4216
Titre abrégé: Prog Neuropsychopharmacol Biol Psychiatry
Pays: England
ID NLM: 8211617

Informations de publication

Date de publication:
08 03 2022
Historique:
received: 11 05 2021
revised: 22 10 2021
accepted: 24 10 2021
pubmed: 1 11 2021
medline: 25 2 2022
entrez: 31 10 2021
Statut: ppublish

Résumé

Emotion recognition constitutes a pivotal process of social cognition. It involves decoding social cues (e.g., facial expressions) to maximise social adjustment. Current theoretical models posit the relationship between social withdrawal factors (social disengagement, lack of social interactions and loneliness) and emotion decoding. To investigate the role of social withdrawal in patients with schizophrenia (SZ) or probable Alzheimer's disease (AD), neuropsychiatric conditions associated with social dysfunction. A sample of 156 participants was recruited: schizophrenia patients (SZ; n = 53), Alzheimer's disease patients (AD; n = 46), and two age-matched control groups (SZc, n = 29; ADc, n = 28). All participants provided self-report measures of loneliness and social functioning, and completed a facial emotion detection task. Neuropsychiatric patients (both groups) showed poorer performance in detecting both positive and negative emotions compared with their healthy counterparts (p < .01). Social withdrawal was associated with higher accuracy in negative emotion detection, across all groups. Additionally, neuropsychiatric patients with higher social withdrawal showed lower positive emotion misclassification. Our findings help to detail the similarities and differences in social function and facial emotion recognition in two disorders rarely studied in parallel, AD and SZ. Transdiagnostic patterns in these results suggest that social withdrawal is associated with heightened sensitivity to negative emotion expressions, potentially reflecting hypervigilance to social threat. Across the neuropsychiatric groups specifically, this hypervigilance associated with social withdrawal extended to positive emotion expressions, an emotional-cognitive bias that may impact social functioning in people with severe mental illness.

Sections du résumé

BACKGROUND
Emotion recognition constitutes a pivotal process of social cognition. It involves decoding social cues (e.g., facial expressions) to maximise social adjustment. Current theoretical models posit the relationship between social withdrawal factors (social disengagement, lack of social interactions and loneliness) and emotion decoding.
OBJECTIVE
To investigate the role of social withdrawal in patients with schizophrenia (SZ) or probable Alzheimer's disease (AD), neuropsychiatric conditions associated with social dysfunction.
METHODS
A sample of 156 participants was recruited: schizophrenia patients (SZ; n = 53), Alzheimer's disease patients (AD; n = 46), and two age-matched control groups (SZc, n = 29; ADc, n = 28). All participants provided self-report measures of loneliness and social functioning, and completed a facial emotion detection task.
RESULTS
Neuropsychiatric patients (both groups) showed poorer performance in detecting both positive and negative emotions compared with their healthy counterparts (p < .01). Social withdrawal was associated with higher accuracy in negative emotion detection, across all groups. Additionally, neuropsychiatric patients with higher social withdrawal showed lower positive emotion misclassification.
CONCLUSIONS
Our findings help to detail the similarities and differences in social function and facial emotion recognition in two disorders rarely studied in parallel, AD and SZ. Transdiagnostic patterns in these results suggest that social withdrawal is associated with heightened sensitivity to negative emotion expressions, potentially reflecting hypervigilance to social threat. Across the neuropsychiatric groups specifically, this hypervigilance associated with social withdrawal extended to positive emotion expressions, an emotional-cognitive bias that may impact social functioning in people with severe mental illness.

Identifiants

pubmed: 34718073
pii: S0278-5846(21)00222-0
doi: 10.1016/j.pnpbp.2021.110463
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

110463

Informations de copyright

Copyright © 2021. Published by Elsevier Inc.

Auteurs

Alejandro de la Torre-Luque (A)

Institute of Education & Child Studies, Section Forensic Family & Youth Care, Leiden University, The Netherlands; Amsterdam UMC, Vrije Universiteit and GGZ inGeest Research & Innovation, The Netherlands. Electronic address: af.delatorre@ucm.es.

Alba Viera-Campos (A)

La Princesa University Hospital, Spain.

Amy C Bilderbeck (AC)

P1vital Ltd., UK.

Maria Teresa Carreras (MT)

La Princesa University Hospital, Spain.

Jose Vivancos (J)

La Princesa University Hospital, Spain.

Covadonga M Diaz-Caneja (CM)

Institute of Education & Child Studies, Section Forensic Family & Youth Care, Leiden University, The Netherlands; Amsterdam UMC, Vrije Universiteit and GGZ inGeest Research & Innovation, The Netherlands; Gregorio Marañon University Hospital, Spain.

Moji Aghajani (M)

Amsterdam UMC, Vrije Universiteit and GGZ inGeest Research & Innovation, the Netherlands.

Ilja M J Saris (IMJ)

Amsterdam UMC, Vrije Universiteit and GGZ inGeest Research & Innovation, the Netherlands.

Andreea Raslescu (A)

P1vital Ltd., UK.

Asad Malik (A)

P1vital Ltd., UK.

Jenna Clark (J)

University of Nottingham, UK.

Brenda W J H Penninx (BWJH)

Amsterdam UMC, Vrije Universiteit and GGZ inGeest Research & Innovation, the Netherlands.

Nic van der Wee (N)

Leiden University Medical Centre, the Netherlands.

Inge Winter-van Rossum (IW)

King's College London, UK.

Bernd Sommer (B)

Boehringer Ingelheim International, Germany.

Hugh Marston (H)

Eli Lilly and Company Ltd., UK.

Gerard R Dawson (GR)

P1vital Ltd., UK.

Martien J Kas (MJ)

University of Groningen, the Netherlands.

Jose Luis Ayuso-Mateos (JL)

Amsterdam UMC, Vrije Universiteit and GGZ inGeest Research & Innovation, The Netherlands; La Princesa University Hospital, Spain.

Celso Arango (C)

Institute of Education & Child Studies, Section Forensic Family & Youth Care, Leiden University, The Netherlands; Amsterdam UMC, Vrije Universiteit and GGZ inGeest Research & Innovation, The Netherlands; Gregorio Marañon University Hospital, Spain.

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