The evaluation of patient demographics, etiologies and apraclonidine test results in adult Horner's syndrome.


Journal

International ophthalmology
ISSN: 1573-2630
Titre abrégé: Int Ophthalmol
Pays: Netherlands
ID NLM: 7904294

Informations de publication

Date de publication:
Apr 2022
Historique:
received: 19 02 2021
accepted: 21 10 2021
pubmed: 1 11 2021
medline: 13 4 2022
entrez: 31 10 2021
Statut: ppublish

Résumé

We aimed to demonstrate the patient demographics, etiologies and apraclonidine test results in adult Horner's syndrome. This retrospective study was performed by the analysis of medical data of patients who were given 0.5% apraclonidine test. Patients' past medical history, demographic data, etiologies, accompanying neurological findings and pharmacological test results were assessed. Forty patients (21 females and 19 males) with a mean age of 50.3 ± 11.6 years were evaluated. Apraclonidine 0.5% test was positive in 37 patients (92.5%). An etiology could be identified in 20 patients (central [9 patients, 45%], preganglionic [9 patients, 45%] and postganglionic [2 patients, 10%]). Neurological findings accompanying Horner's syndrome were present in 8 patients. Despite detailed investigations, in a significant number of patients with Horner's syndrome an underlying cause may not be detected. Among the identifiable lesions, central and preganglionic involvements are still the first leading causes of Horner's syndrome. In addition, apraclonidine test may not be positive in all patients and a negative response does not exclude Horner's syndrome.

Identifiants

pubmed: 34718919
doi: 10.1007/s10792-021-02109-0
pii: 10.1007/s10792-021-02109-0
doi:

Substances chimiques

apraclonidine 843CEN85DI
Clonidine MN3L5RMN02

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1233-1239

Subventions

Organisme : Scientific Research Project Coordination Unit of İzmir Democracy University. Project number:TPF-20H04.
ID : TPF-20H04

Informations de copyright

© 2021. The Author(s), under exclusive licence to Springer Nature B.V.

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Auteurs

Dilek Top Karti (D)

Department of Neurology, Bozyaka Training and Research Hospital, Izmir, Turkey.

Omer Karti (O)

Department of Ophthalmology, İzmir Democracy Univesity, Güzelyalı Konak /İZMİR, Mehmet Ali Akman Mahallesi, 13. Sokak No:2, Izmir, Turkey. kartiomer@gmail.com.

Gulsum Saruhan Durmaz (G)

Department of Neurology, Ege University Medical Faculty, Izmir, Turkey.

Figen Gokcay (F)

Department of Neurology, Ege University Medical Faculty, Izmir, Turkey.

Nese Celebisoy (N)

Department of Neurology, Ege University Medical Faculty, Izmir, Turkey.

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