COVID-19 vaccine hesitancy in underserved communities of North Carolina.


Journal

PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081

Informations de publication

Date de publication:
2021
Historique:
received: 04 03 2021
accepted: 21 07 2021
entrez: 1 11 2021
pubmed: 2 11 2021
medline: 16 11 2021
Statut: epublish

Résumé

In the United States, underserved communities including Blacks and Latinx are disproportionately affected by COVID-19. This study sought to estimate the prevalence of COVID-19 vaccine hesitancy, describe attitudes related to vaccination, and identify correlates among historically marginalized populations across 9 counties in North Carolina. We conducted a cross-sectional survey distributed at free COVID-19 testing events in underserved rural and urban communities from August 27 -December 15, 2020. Vaccine hesitancy was defined as the response of "no" or "don't know/not sure" to whether the participant would get the COVID-19 vaccine as soon as it became available. The sample comprised 948 participants including 27.7% Whites, 59.6% Blacks, 12.7% Latinx, and 63% female. 32% earned <$20K annually, 60% owned a computer and ~80% had internet access at home. The prevalence of vaccine hesitancy was 68.9% including 62.7%, 74%, and 59.5% among Whites, Blacks, and Latinx, respectively. Between September and December, the largest decline in vaccine hesitancy occurred among Whites (27.5 percentage points), followed by Latinx (17.6) and only 12.0 points among Blacks. 51.2% of respondents reported vaccine safety concerns, 23.7% wanted others to get vaccinated first, and 63.1% would trust health care providers about the COVID-19 vaccine. Factors associated with hesitancy in multivariable logistic regression included being female (OR = 1.90 95%CI [1.36, 2.64]), being Black (OR = 1.68 1.16, 2.45]), calendar month (OR = 0.76 [0.63, 0.92]), safety concerns (OR = 4.28 [3.06, 5.97]), and government distrust (OR = 3.57 [2.26, 5.63]). This study engaged the community to directly reach underserved minority populations at highest risk of COVID-19 that permitted assessment of vaccine hesitancy (which was much higher than national estimates), driven in part by distrust, and safety concerns.

Sections du résumé

BACKGROUND
In the United States, underserved communities including Blacks and Latinx are disproportionately affected by COVID-19. This study sought to estimate the prevalence of COVID-19 vaccine hesitancy, describe attitudes related to vaccination, and identify correlates among historically marginalized populations across 9 counties in North Carolina.
METHODS
We conducted a cross-sectional survey distributed at free COVID-19 testing events in underserved rural and urban communities from August 27 -December 15, 2020. Vaccine hesitancy was defined as the response of "no" or "don't know/not sure" to whether the participant would get the COVID-19 vaccine as soon as it became available.
RESULTS
The sample comprised 948 participants including 27.7% Whites, 59.6% Blacks, 12.7% Latinx, and 63% female. 32% earned <$20K annually, 60% owned a computer and ~80% had internet access at home. The prevalence of vaccine hesitancy was 68.9% including 62.7%, 74%, and 59.5% among Whites, Blacks, and Latinx, respectively. Between September and December, the largest decline in vaccine hesitancy occurred among Whites (27.5 percentage points), followed by Latinx (17.6) and only 12.0 points among Blacks. 51.2% of respondents reported vaccine safety concerns, 23.7% wanted others to get vaccinated first, and 63.1% would trust health care providers about the COVID-19 vaccine. Factors associated with hesitancy in multivariable logistic regression included being female (OR = 1.90 95%CI [1.36, 2.64]), being Black (OR = 1.68 1.16, 2.45]), calendar month (OR = 0.76 [0.63, 0.92]), safety concerns (OR = 4.28 [3.06, 5.97]), and government distrust (OR = 3.57 [2.26, 5.63]).
CONCLUSIONS
This study engaged the community to directly reach underserved minority populations at highest risk of COVID-19 that permitted assessment of vaccine hesitancy (which was much higher than national estimates), driven in part by distrust, and safety concerns.

Identifiants

pubmed: 34723973
doi: 10.1371/journal.pone.0248542
pii: PONE-D-21-07150
pmc: PMC8559933
doi:

Substances chimiques

COVID-19 Vaccines 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0248542

Subventions

Organisme : NIMHD NIH HHS
ID : R01 MD012767
Pays : United States
Organisme : NIMHD NIH HHS
ID : U54 MD012392
Pays : United States

Commentaires et corrections

Type : UpdateOf

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

Références

Clin Infect Dis. 2011 Apr 1;52(7):911-6
pubmed: 21427399
Vaccines (Basel). 2021 Feb 03;9(2):
pubmed: 33546165
Health Commun. 2020 Dec;35(14):1707-1710
pubmed: 33081500
MMWR Morb Mortal Wkly Rep. 2021 Jan 01;69(5152):1657-1660
pubmed: 33382671
J Relig Health. 2012 Mar;51(1):148-60
pubmed: 19960262
Soc Sci Med. 2021 Jan;268:113554
pubmed: 33308911
Ann Intern Med. 2020 Dec 15;173(12):964-973
pubmed: 32886525
Vaccine. 2020 Sep 29;38(42):6500-6507
pubmed: 32863069
Vaccines (Basel). 2020 Oct 03;8(4):
pubmed: 33022917
Vaccine. 2021 Feb 12;39(7):1080-1086
pubmed: 33461833
J Infect Dis. 2010 Jun 1;201(11):1607-10
pubmed: 20402594
J Natl Med Assoc. 2010 Sep;102(9):823-31
pubmed: 20922927
J Infect. 2020 Jun;80(6):e32-e33
pubmed: 32209383
Front Psychol. 2020 Oct 19;11:575950
pubmed: 33192883
Vaccine. 2015 Aug 14;33(34):4161-4
pubmed: 25896383
Vaccine. 2021 Jan 29;39(5):825-829
pubmed: 33390295
J Community Health. 2021 Apr;46(2):270-277
pubmed: 33389421
JAMA. 2020 Dec 29;:
pubmed: 33372943
N Engl J Med. 2021 Feb 4;384(5):403-416
pubmed: 33378609
JAMA. 2021 Jan 12;325(2):123-124
pubmed: 33331845
Soc Sci Med. 2021 Mar;272:113638
pubmed: 33414032
JAMA. 2020 Oct 20;324(15):1562-1564
pubmed: 33044483
JAMA Netw Open. 2020 Oct 1;3(10):e2025594
pubmed: 33079199
medRxiv. 2020 Nov 30;:
pubmed: 33269354
JAMA. 2020 Jun 23;323(24):2466-2467
pubmed: 32391864
N Engl J Med. 2020 Dec 31;383(27):2603-2615
pubmed: 33301246
N Engl J Med. 2021 Feb 18;384(7):e23
pubmed: 33406324

Auteurs

Irene A Doherty (IA)

Julius L. Chambers Biomedical Biotechnology Research Institute, North Carolina Central University, Durham, NC, United States of America.

William Pilkington (W)

Julius L. Chambers Biomedical Biotechnology Research Institute, North Carolina Central University, Durham, NC, United States of America.

Laurin Brown (L)

Julius L. Chambers Biomedical Biotechnology Research Institute, North Carolina Central University, Durham, NC, United States of America.

Victoria Billings (V)

Julius L. Chambers Biomedical Biotechnology Research Institute, North Carolina Central University, Durham, NC, United States of America.

Undi Hoffler (U)

Division of Research and Sponsored Programs, North Carolina Central University, Durham, NC, United States of America.

Lisa Paulin (L)

Department of Mass Communication, North Carolina Central University, Durham, NC, United States of America.

K Sean Kimbro (KS)

Julius L. Chambers Biomedical Biotechnology Research Institute, North Carolina Central University, Durham, NC, United States of America.

Brittany Baker (B)

Department of Nursing, North Carolina Central University, Durham, NC, United States of America.

Tianduo Zhang (T)

Department of Mass Communication, North Carolina Central University, Durham, NC, United States of America.

Tracie Locklear (T)

Department of Pharmaceutical Sciences, North Carolina Central University, Durham, NC, United States of America.

Seronda Robinson (S)

Department of Public Health Education, North Carolina Central University, Durham, NC, United States of America.

Deepak Kumar (D)

Julius L. Chambers Biomedical Biotechnology Research Institute, North Carolina Central University, Durham, NC, United States of America.
Department of Pharmaceutical Sciences, North Carolina Central University, Durham, NC, United States of America.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH