A case-controlled investigation of risk factors associated with molar incisor hypomineralization (MIH) in 8-12 year-old children living in Chandigarh, India.


Journal

European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry
ISSN: 1996-9805
Titre abrégé: Eur Arch Paediatr Dent
Pays: England
ID NLM: 101277157

Informations de publication

Date de publication:
Feb 2022
Historique:
received: 25 03 2021
accepted: 31 08 2021
pubmed: 3 11 2021
medline: 19 3 2022
entrez: 2 11 2021
Statut: ppublish

Résumé

Despite mounting evidence in favour of various perinatal risk factors for occurrence of MIH, verification of these remains doubtful because of lack of documented proof. The present study was aimed at examining the putative risk factors for MIH based on hospital-maintained records assessment. A total of 3176, 8-12 year-old children were screened for MIH using EAPD criteria (2003). Of these, risk factor analysis was carried out for 104 MIH affected and 211 non-MIH affected children with complete peri-natal medical records maintained up to 3 year post-birth. Chi-square test was used for risk factor comparison, while significance was assessed using logistic regression. Prevalence of MIH in study population was 11.72% (372/3176). Various pre-natal, natal and post-natal risk factors including intra-uterine growth retardation (6.7 vs. 1.4%); maternal anaemia (10.6 vs. 3.8%) and neonatal jaundice (29.8 vs. 14.2%) were significantly higher in the MIH group. Furthermore, pre-term birth (OR 3.01), low birth weight (OR 2.37), more than three pyrogenic episodes (OR 7.61) and consumption of Amoxicillin Clavulanate (OR 3.01) were significantly associated with higher risk of developing MIH. Pre and post-natal risk factors showed a moderate to high association for occurrence of MIH although social and nutritional factors had a lesser association.

Identifiants

pubmed: 34725798
doi: 10.1007/s40368-021-00665-8
pii: 10.1007/s40368-021-00665-8
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

97-107

Informations de copyright

© 2021. European Academy of Paediatric Dentistry.

Références

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Auteurs

S Mariam (S)

Unit of Pedodontics and Preventive Dentistry, Oral Health Sciences Centre, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.

A Goyal (A)

Unit of Pedodontics and Preventive Dentistry, Oral Health Sciences Centre, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.

A Dhareula (A)

Unit of Pedodontics and Preventive Dentistry, Oral Health Sciences Centre, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India. dhareulaankita88@gmail.com.
Divisional Railways Hospital, Central Railways, Pune, 411001, Maharashtra, India. dhareulaankita88@gmail.com.

K Gauba (K)

Unit of Pedodontics and Preventive Dentistry, Oral Health Sciences Centre, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.

S K Bhatia (SK)

Unit of Pedodontics and Preventive Dentistry, Oral Health Sciences Centre, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.

A Kapur (A)

Unit of Pedodontics and Preventive Dentistry, Oral Health Sciences Centre, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.

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