CD36 maintains the gastric mucosa and associates with gastric disease.


Journal

Communications biology
ISSN: 2399-3642
Titre abrégé: Commun Biol
Pays: England
ID NLM: 101719179

Informations de publication

Date de publication:
02 11 2021
Historique:
received: 29 03 2021
accepted: 06 10 2021
entrez: 3 11 2021
pubmed: 4 11 2021
medline: 21 12 2021
Statut: epublish

Résumé

The gastric epithelium is often exposed to injurious elements and failure of appropriate healing predisposes to ulcers, hemorrhage, and ultimately cancer. We examined the gastric function of CD36, a protein linked to disease and homeostasis. We used the tamoxifen model of gastric injury in mice null for Cd36 (Cd36

Identifiants

pubmed: 34728772
doi: 10.1038/s42003-021-02765-z
pii: 10.1038/s42003-021-02765-z
pmc: PMC8563937
doi:

Substances chimiques

CD36 Antigens 0
Cd36 protein, mouse 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1247

Subventions

Organisme : NIDDK NIH HHS
ID : R01 DK060022
Pays : United States
Organisme : NHGRI NIH HHS
ID : R01 HG011138
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK101332
Pays : United States
Organisme : NCRR NIH HHS
ID : S10 RR027552
Pays : United States
Organisme : NIDDK NIH HHS
ID : P30 DK056341
Pays : United States
Organisme : NIDDK NIH HHS
ID : P30 DK056338
Pays : United States
Organisme : NCI NIH HHS
ID : R01 CA246208
Pays : United States
Organisme : NIDDK NIH HHS
ID : P30 DK020579
Pays : United States
Organisme : NIA NIH HHS
ID : R56 AG068026
Pays : United States
Organisme : NHGRI NIH HHS
ID : R35 HG010718
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK048370
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM140287
Pays : United States
Organisme : Medical Research Council
ID : MC_PC_17228
Pays : United Kingdom
Organisme : NCI NIH HHS
ID : R01 CA239645
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK094989
Pays : United States
Organisme : NIDDK NIH HHS
ID : P30 DK052574
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK111175
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK105129
Pays : United States
Organisme : Medical Research Council
ID : MC_QA137853
Pays : United Kingdom

Informations de copyright

© 2021. The Author(s).

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Auteurs

Miriam Jacome-Sosa (M)

Center for Human Nutrition, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA. mjacome@wustl.edu.

Zhi-Feng Miao (ZF)

Department of Surgical Oncology, Laboratory of Precision Diagnosis and Treatment of Gastrointestinal Tumors, First Hospital of China Medical University, Shenyang, China.
Division of Gastroenterology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.

Vivek S Peche (VS)

Center for Human Nutrition, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.

Edward F Morris (EF)

Center for Human Nutrition, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.

Ramkumar Narendran (R)

Center for Human Nutrition, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.

Kathryn M Pietka (KM)

Center for Human Nutrition, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.

Dmitri Samovski (D)

Center for Human Nutrition, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.

Hei-Yong G Lo (HG)

Division of Gastroenterology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.

Terri Pietka (T)

Center for Human Nutrition, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.

Andrea Varro (A)

Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

Latisha Love-Gregory (L)

Department of Pathology & Immunology, Washington University School of Medicine, St Louis, MO, USA.

James R Goldenring (JR)

Departments of Surgery and Cell and Developmental Biology, Vanderbilt University Medical Center and VA Medical Center, Nashville, TN, USA.

Ondrej Kuda (O)

Institute of Physiology, Czech Academy of Sciences, Videnska 1083, 14220 Prague 4, Czech Republic.

Eric R Gamazon (ER)

Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
MRC Epidemiology Unit, University of Cambridge, Cambridge, UK.

Jason C Mills (JC)

Gastroenterology & Hepatology Section, Departments of Medicine and of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA. Jason.Mills@bcm.edu.

Nada A Abumrad (NA)

Center for Human Nutrition, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA. nabumrad@wustl.edu.
Department of Cell Biology and Physiology, Washington University School of Medicine, St. Louis, MO, USA. nabumrad@wustl.edu.

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Classifications MeSH