Primary Central Nervous System Lymphoma With Systemic Recurrence.
central nervous system tumor
oncology
pcnsl
primary central nervous system lymphoma (pcnsl)
primary cns lymphoma
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
Sep 2021
Sep 2021
Historique:
accepted:
29
09
2021
entrez:
3
11
2021
pubmed:
4
11
2021
medline:
4
11
2021
Statut:
epublish
Résumé
Primary central nervous system lymphoma (PCNSL) is an extranodal non-Hodgkin's lymphoma confined to the brain, leptomeninges, spinal cord, or eyes without systemic involvement. Nearly half of patients with PCNSL who achieve complete remission, relapse within five years. The majority of patients who relapse have a local recurrence. Systemic relapse, however, is much rarer. Here, we report a rare case of a 70-year-old male diagnosed with PCNSL who relapsed systemically nearly 1.5 years after achieving complete remission. His treatment consisted of chemoimmunotherapy and targeted therapy followed by an autologous transplant. Currently, there is no standard of care for systemic relapse of PCNSL. This multiagent treatment modality may be one such option for salvage therapy.
Identifiants
pubmed: 34729283
doi: 10.7759/cureus.18406
pmc: PMC8555944
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e18406Informations de copyright
Copyright © 2021, Pandravada et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
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