Far-advanced Colorectal Liver Metastases Successfully Managed With Modified ALPPS and Radiofrequency Ablation in Combination With Chemotherapy.
Adenocarcinoma
/ diagnostic imaging
Antineoplastic Combined Chemotherapy Protocols
/ adverse effects
Chemotherapy, Adjuvant
Colorectal Neoplasms
/ pathology
Colostomy
Hepatectomy
Humans
Ligation
Liver Neoplasms
/ diagnostic imaging
Male
Middle Aged
Neoadjuvant Therapy
Neoplasm Staging
Portal Vein
/ surgery
Radiofrequency Ablation
Treatment Outcome
Liver partition
colorectal liver metastases
multidisciplinary treatment
portal vein ligation
radiofrequency ablation
staged hepatectomy
systemic chemotherapy
Journal
Anticancer research
ISSN: 1791-7530
Titre abrégé: Anticancer Res
Pays: Greece
ID NLM: 8102988
Informations de publication
Date de publication:
Nov 2021
Nov 2021
Historique:
received:
06
09
2021
revised:
14
10
2021
accepted:
18
10
2021
entrez:
4
11
2021
pubmed:
5
11
2021
medline:
16
11
2021
Statut:
ppublish
Résumé
Large numbers of synchronous colorectal liver metastases are associated with poor prognosis. A 47-year-old male patient with rectal cancer and unresectable colorectal liver metastases (over 15 cm in diameter and over 30 metastases) was treated with a multidisciplinary treatment including systemic chemotherapy with mFOLFOX6/panitumumab and surgical therapies (colostomy, modified associating liver partition and portal vein ligation for staged hepatectomy together with radiofrequency ablation). For solitary recurrent colorectal liver metastases, percutaneous radiofrequency ablation with chemoembolization and open radiofrequency ablation in combination with the same systemic chemotherapy was performed. Since the diagnosis 3 years ago, he has been leading a good quality of life, free of any tumor or treatment. For patients with far-advanced but liver-only colorectal liver metastases, surgical therapy, systemic chemotherapy, and interventional treatment can be important for achieving good prognosis.
Sections du résumé
BACKGROUND
BACKGROUND
Large numbers of synchronous colorectal liver metastases are associated with poor prognosis.
CASE REPORT
METHODS
A 47-year-old male patient with rectal cancer and unresectable colorectal liver metastases (over 15 cm in diameter and over 30 metastases) was treated with a multidisciplinary treatment including systemic chemotherapy with mFOLFOX6/panitumumab and surgical therapies (colostomy, modified associating liver partition and portal vein ligation for staged hepatectomy together with radiofrequency ablation). For solitary recurrent colorectal liver metastases, percutaneous radiofrequency ablation with chemoembolization and open radiofrequency ablation in combination with the same systemic chemotherapy was performed. Since the diagnosis 3 years ago, he has been leading a good quality of life, free of any tumor or treatment.
CONCLUSION
CONCLUSIONS
For patients with far-advanced but liver-only colorectal liver metastases, surgical therapy, systemic chemotherapy, and interventional treatment can be important for achieving good prognosis.
Identifiants
pubmed: 34732462
pii: 41/11/5855
doi: 10.21873/anticanres.15405
doi:
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
5855-5861Informations de copyright
Copyright © 2021 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.