Association between Hypomagnesemia, COVID-19, Respiratory Tract and Lung Disease.

COVID-19 Effects Lung diseases Magnesium Magnesium deficiency Obesity

Journal

The open respiratory medicine journal
ISSN: 1874-3064
Titre abrégé: Open Respir Med J
Pays: United Arab Emirates
ID NLM: 101480481

Informations de publication

Date de publication:
2021
Historique:
received: 15 01 2021
revised: 26 04 2021
accepted: 07 06 2021
entrez: 4 11 2021
pubmed: 5 11 2021
medline: 5 11 2021
Statut: epublish

Résumé

The complexity of COVID-19 is also related to the multiple molecular pathways triggered by SARS-CoV-2, which is able to cause type I pneumocyte death, trigger intravascular coagulation, interfere with the renin-angiotensin system, dysregulate iron metabolism, ending with the insurgence of a cytokine storm which may lead to death. Old adults with obesity, hypertension, and diabetes are among the high-risk category groups more prone to SARS-CoV-2 infection. Magnesium has been reported to play a major role both in physiology and in pathology, particularly in elderly people, regulating cytotoxic functions of natural killer (NK) cells and CD8+ T lymphocytes. In spite of the absence of controlled trials, the possibility of magnesium supplementation for supportive treatment in patients with COVID-19 should be encouraged. This could be useful in all phases of the COVID-19 disease.

Identifiants

pubmed: 34733373
doi: 10.2174/1874306402115010043
pii: TORMJ-15-43
pmc: PMC8493831
doi:

Types de publication

Editorial

Langues

eng

Pagination

43-45

Informations de copyright

© 2021 Faa et al.

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Auteurs

Gavino Faa (G)

Division of Pathology, Department of Medical Sciences and Public Health, University Hospital San Giovanni di Dio, Cagliari, Italy.
Department of Biology, College of Science and Technology, Temple University, Philadelphia, PA, USA.

Luca Saba (L)

Department of Medical Imaging, Azienda Ospedaliero Universitaria (AOU) of Cagliari-Polo di Monserrato, Cagliari, Italy.

Daniela Fanni (D)

Division of Pathology, Department of Medical Sciences and Public Health, University Hospital San Giovanni di Dio, Cagliari, Italy.
Department of Biology, College of Science and Technology, Temple University, Philadelphia, PA, USA.

Goce Kalcev (G)

International Ph.D. in Innovation Sciences and Technologies, University of Cagliari, Cagliari, Italy.

Mauro Carta (M)

Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.

Classifications MeSH