Antiphospholipid-negative Sneddon's syndrome: A comprehensive overview of a rare entity.

Antiphospholipid Syndrome / complications Diagnosis, Differential Humans Livedo Reticularis / diagnosis Sneddon Syndrome / complications
Antiphospholipid Cerebral infarction Livedo racemosa Sneddon's syndrome

Journal

Annales de dermatologie et de venereologie
ISSN: 0151-9638
Titre abrégé: Ann Dermatol Venereol
Pays: France
ID NLM: 7702013

Informations de publication

Date de publication:
Mar 2022
Historique:
received: 05 01 2021
revised: 26 05 2021
accepted: 04 08 2021
pubmed: 7 11 2021
medline: 23 2 2022
entrez: 6 11 2021
Statut: ppublish

Résumé

The term Sneddon's syndrome (SS) has been used since 1965 to describe a vasculopathy characterized by a combination of cerebrovascular disease with livedo racemosa. SS may be classified as antiphospholipid+ (aPL+) or antiphospholipid- (aPL-). Little is known about aPL- SS; in this review we describe the epidemiology and pathogenesis of aPL- SS, as well as the clinical and histologic features. We discuss recent findings in terms of neurologic and cardiac involvement. Moreover, differential diagnoses of conditions that may present with both livedo racemosa and stroke are discussed. Finally, we discuss real-life practical issues such as the initial investigations to be performed, long-term follow-up, and therapeutic management of aPL- SS patients.

Identifiants

DOI: 10.1016/j.annder.2021.08.007 PMID: 34740467
pubmed: 34740467
pii: S0151-9638(21)00096-X
doi: 10.1016/j.annder.2021.08.007
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

3-13

Informations de copyright

Copyright © 2021 Elsevier Masson SAS. All rights reserved.

Auteurs

F Assan (F)

Sorbonne University, Faculté de Médecine Sorbonne Université, AP-HP, Service de Dermatologie et Allergologie, Hôpital Tenon, 75020 Paris, France.

L Bottin (L)

Sorbonne University, Faculté de Médecine Sorbonne Université, AP-HP, Service de Neurologie, Hôpital Saint-Antoine, 75012 Paris, France.

C Francès (C)

Sorbonne University, Faculté de Médecine Sorbonne Université, AP-HP, Service de Dermatologie et Allergologie, Hôpital Tenon, 75020 Paris, France.

P Moguelet (P)

Sorbonne University, Faculté de Médecine Sorbonne Université, AP-HP, Service de Pathologie, Hôpital Tenon, 75020 Paris, France.

S Tavolaro (S)

Sorbonne University, Faculté de Médecine Sorbonne Université, AP-HP, Service de Radiologie, Hôpital Tenon, 75020 Paris, France.

A Barbaud (A)

Sorbonne University, Faculté de Médecine Sorbonne Université, AP-HP, Service de Dermatologie et Allergologie, Hôpital Tenon, 75020 Paris, France.

D de Zuttere (D)

Service d'Explorations Fonctionnelles, Hôpital Franco-Britannique, 92300 Levallois-Perret, France.

S Alamowitch (S)

Sorbonne University, Faculté de Médecine Sorbonne Université, AP-HP, Service de Neurologie, Hôpital Saint-Antoine, 75012 Paris, France.

F Chasset (F)

Sorbonne University, Faculté de Médecine Sorbonne Université, AP-HP, Service de Dermatologie et Allergologie, Hôpital Tenon, 75020 Paris, France. Electronic address: francois.chasset@aphp.fr.

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Classifications MeSH

questionsmedicales.fr › Maladies du système immunitaire › Maladies auto-immunes › Syndrome des anticorps antiphospholipides › Antiphospholipid-negative Sneddon's syndrome:...
questionsmedicales.fr › Diagnostic › Diagnostic différentiel › Antiphospholipid-negative Sneddon's syndrome:...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Antiphospholipid-negative Sneddon's syndrome:...
questionsmedicales.fr › États, signes et symptômes pathologiques › Signes et symptômes › Manifestations cutanées › Livedo réticulaire › Antiphospholipid-negative Sneddon's syndrome:...
questionsmedicales.fr › Maladies de la peau et du tissu conjonctif › Maladies de la peau › Dermatoses vasculaires › Syndrome de Sneddon › Antiphospholipid-negative Sneddon's syndrome:...