Social isolation, social support, and loneliness and their relationship with cognitive health and dementia.
age factors
aged
aged 80 and over
ageing
cognition
cognitive health
dementia
geriatrics
interpersonal relations
loneliness
older adult
social connection
social interaction
social isolation
social support
Journal
International journal of geriatric psychiatry
ISSN: 1099-1166
Titre abrégé: Int J Geriatr Psychiatry
Pays: England
ID NLM: 8710629
Informations de publication
Date de publication:
05 Nov 2021
05 Nov 2021
Historique:
received:
05
07
2021
accepted:
31
10
2021
pubmed:
7
11
2021
medline:
7
11
2021
entrez:
6
11
2021
Statut:
aheadofprint
Résumé
Poor social health is prevalent in older adults and may be associated with worse cognition, and increased dementia risk. The aim of this study was to determine whether social isolation, social support and loneliness are independently associated with cognitive function and incident dementia over 5 years in older adults, and to investigate potential gender differences. Participants were 11,498 community-dwelling relatively healthy Australians aged 70-94, in the ASPREE Longitudinal Study of Older Persons (ALSOP). Social isolation, social support, loneliness and cognitive function were assessed through self-report. Outcomes examined were cognitive decline (>1.5 SD decline in cognitive performance since baseline) and incident dementia (adjudicated according to DSM-IV criteria). Most participants self-reported good social health (92%) with very few socially isolated (2%), with low social support (2%) or lonely (5%). Among women, social isolation and low social support were consistently associated with lower cognitive function (e.g., social support and cognition β = -1.17, p < 0.001). No consistent longitudinal associations were observed between baseline social health and cognitive decline (over median 3.1 years) or incident dementia (over median 4.4 years; social isolation: HR = 1.00, p = 0.99; low social support: HR = 1.79, p = 0.11; loneliness: HR = 0.72, p = 0.34 among women and men). Our study provides evidence that social isolation and a low social support are associated with worse cognitive function in women, but not men. Social health did not predict incident cognitive decline or dementia, but we lacked power to stratify dementia analyses by gender.
Sections du résumé
BACKGROUND
BACKGROUND
Poor social health is prevalent in older adults and may be associated with worse cognition, and increased dementia risk. The aim of this study was to determine whether social isolation, social support and loneliness are independently associated with cognitive function and incident dementia over 5 years in older adults, and to investigate potential gender differences.
METHODS
METHODS
Participants were 11,498 community-dwelling relatively healthy Australians aged 70-94, in the ASPREE Longitudinal Study of Older Persons (ALSOP). Social isolation, social support, loneliness and cognitive function were assessed through self-report. Outcomes examined were cognitive decline (>1.5 SD decline in cognitive performance since baseline) and incident dementia (adjudicated according to DSM-IV criteria).
RESULTS
RESULTS
Most participants self-reported good social health (92%) with very few socially isolated (2%), with low social support (2%) or lonely (5%). Among women, social isolation and low social support were consistently associated with lower cognitive function (e.g., social support and cognition β = -1.17, p < 0.001). No consistent longitudinal associations were observed between baseline social health and cognitive decline (over median 3.1 years) or incident dementia (over median 4.4 years; social isolation: HR = 1.00, p = 0.99; low social support: HR = 1.79, p = 0.11; loneliness: HR = 0.72, p = 0.34 among women and men).
CONCLUSION
CONCLUSIONS
Our study provides evidence that social isolation and a low social support are associated with worse cognitive function in women, but not men. Social health did not predict incident cognitive decline or dementia, but we lacked power to stratify dementia analyses by gender.
Identifiants
pubmed: 34741340
doi: 10.1002/gps.5644
pmc: PMC9068834
mid: NIHMS1764005
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NIA NIH HHS
ID : U19 AG062682
Pays : United States
Organisme : NIA NIH HHS
ID : U01 AG029824
Pays : United States
Organisme : National Health and Medical Research Council of Australia
ID : 1127060
Organisme : National Heart Foundation of Australia
ID : 101927
Organisme : Victorian Cancer Agency
ID : 2009001512
Organisme : Monash University
Organisme : Wicking Trust/Mason foundation (ANZ trustees)
ID : 2012001813
Organisme : National Health and Medical Research Council of Australia
ID : 334047
Organisme : US National Institute on Aging
ID : U01AG029824
Organisme : NCI NIH HHS
Pays : United States
Informations de copyright
© 2021 John Wiley & Sons, Ltd.
Références
Psychol Aging. 1995 Dec;10(4):578-89
pubmed: 8749585
Eur J Ageing. 2011 Mar;8(1):31-38
pubmed: 21475393
J Gerontol B Psychol Sci Soc Sci. 2003 Mar;58(2):S93-S100
pubmed: 12646598
Sci Rep. 2016 Sep 16;6:33486
pubmed: 27633756
Aging Ment Health. 2020 Jan;24(1):110-118
pubmed: 30345800
Soc Sci Med. 2000 Sep;51(6):843-57
pubmed: 10972429
Arch Gen Psychiatry. 2007 Feb;64(2):234-40
pubmed: 17283291
Arch Clin Neuropsychol. 2008 May;23(3):229-41
pubmed: 18339515
J Gerontol A Biol Sci Med Sci. 2021 Oct 13;76(11):1997-2006
pubmed: 33963758
Z Gerontol Geriatr. 2002 Dec;35(6):575-81
pubmed: 12491004
Aging Ment Health. 2020 Jun;24(6):889-897
pubmed: 30729792
Health Psychol. 2001 Jul;20(4):243-55
pubmed: 11515736
Int J Geriatr Psychiatry. 2017 Jun;32(6):664-674
pubmed: 27246181
Soc Psychiatry Psychiatr Epidemiol. 2019 Sep;54(9):1079-1088
pubmed: 30863870
Am J Public Health. 2008 Jul;98(7):1215-20
pubmed: 18511736
Aging Ment Health. 2017 Feb;21(2):133-146
pubmed: 26327492
Int J Geriatr Psychiatry. 2020 Jul;35(7):794-801
pubmed: 32250480
Int J Epidemiol. 2016 Aug;45(4):1169-1206
pubmed: 27272181
J Gerontol B Psychol Sci Soc Sci. 2005 Nov;60(6):P320-P330
pubmed: 16260706
J Gerontol B Psychol Sci Soc Sci. 2020 Aug 13;75(7):1414-1422
pubmed: 30365023
J Adv Nurs. 1985 Nov;10(6):533-7
pubmed: 3853568
Med Care. 1977 May;15(5 SUPPL):47-58
pubmed: 853781
J Am Coll Health. 2005 May-Jun;53(6):276-84
pubmed: 15900991
J Alzheimers Dis. 2022;85(1):295-308
pubmed: 34842183
J Cross Cult Gerontol. 2013 Dec;28(4):453-3
pubmed: 24122523
J Prim Prev. 2012 Jun;33(2-3):137-52
pubmed: 22766606
Trends Cogn Sci. 2009 Oct;13(10):447-54
pubmed: 19726219
J Gerontol B Psychol Sci Soc Sci. 2008 Jul;63(4):P241-P244
pubmed: 18689766
Am Psychol. 1994 Apr;49(4):304-13
pubmed: 8203802
PLoS One. 2018 Aug 17;13(8):e0201008
pubmed: 30118489
Neurology. 2005 Jun 14;64(11):1888-92
pubmed: 15955939
Alzheimers Dement. 2018 Sep;14(9):1171-1183
pubmed: 29907423
Eur J Ageing. 2018 Sep 5;16(2):145-154
pubmed: 31139029
J Alzheimers Dis. 2018;66(4):1619-1633
pubmed: 30452410
Psychosom Med. 2013 Feb;75(2):161-70
pubmed: 23362501
Neurology. 2020 Jul 21;95(3):e320-e331
pubmed: 32213642
Lancet Neurol. 2004 Jun;3(6):343-53
pubmed: 15157849
Neurology. 2004 Dec 28;63(12):2322-6
pubmed: 15623694
PLoS One. 2019 Aug 1;14(8):e0220195
pubmed: 31369590
Australas J Ageing. 2018 Mar;37(1):68-73
pubmed: 29232761
Lancet. 2000 Apr 15;355(9212):1315-9
pubmed: 10776744
Soc Sci Med. 2013 Dec;98:116-24
pubmed: 24331889
Am J Epidemiol. 2002 Apr 15;155(8):700-9
pubmed: 11943687
Contemp Clin Trials. 2013 Nov;36(2):555-64
pubmed: 24113028
Int J Epidemiol. 2001 Dec;30(6):1389-96
pubmed: 11821352
Psychogeriatrics. 2017 Jan;17(1):9-16
pubmed: 26858148
Ageing Res Rev. 2015 Jul;22:39-57
pubmed: 25956016
Clin Neuropsychol. 2019 May;33(4):779-797
pubmed: 29976121
N Engl J Med. 2018 Oct 18;379(16):1499-1508
pubmed: 30221596
J Gerontol A Biol Sci Med Sci. 2017 Oct 12;72(11):1586-1593
pubmed: 28329340
Aging Ment Health. 2022 Jul;26(7):1335-1344
pubmed: 34219569
J Gerontol B Psychol Sci Soc Sci. 2004 Nov;59(6):P278-84
pubmed: 15576855
Perspect Psychol Sci. 2015 Mar;10(2):227-37
pubmed: 25910392
Int J Epidemiol. 2019 Aug 1;48(4):1048-1049h
pubmed: 30624660
Endocr Rev. 1986 Aug;7(3):284-301
pubmed: 3527687
Postgrad Med J. 2005 Jun;81(956):343-52
pubmed: 15937198
Syst Rev. 2017 Dec 19;6(1):259
pubmed: 29258596