Effect of Sepsis on Iron Parameters in a Population with High Prevalence of Malnutrition and Iron Deficiency: A Cross-Sectional Case-Control Pilot Study.

Children Ferritin Iron deficiency Low- and middle-income countries Sepsis Soluble transferrin receptor sTfR-ferritin index

Journal

Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion
ISSN: 0971-4502
Titre abrégé: Indian J Hematol Blood Transfus
Pays: India
ID NLM: 9425818

Informations de publication

Date de publication:
Oct 2021
Historique:
received: 11 08 2020
accepted: 05 12 2020
entrez: 8 11 2021
pubmed: 9 11 2021
medline: 9 11 2021
Statut: ppublish

Résumé

There is lack of data on iron metabolism in critically ill sepsis children from population with high prevalence of iron deficiency (ID). The study was designed to study impact of sepsis on iron parameters in children with ID. Sepsis patients (age 6-59 months) and their apparently healthy sibling/cousin as controls were enrolled in this case-control pilot study. Serum iron, TIBC, transferrin saturation, ferritin and sTfR were measured in the two groups. sTfR-Ferritin index was calculated. Patients (

Identifiants

pubmed: 34744344
doi: 10.1007/s12288-020-01393-7
pii: 1393
pmc: PMC8523642
doi:

Types de publication

Journal Article

Langues

eng

Pagination

609-615

Informations de copyright

© Indian Society of Hematology and Blood Transfusion 2021.

Déclaration de conflit d'intérêts

Conflict of interestThe authors declare that they have no conflict of interest.

Références

Indian Pediatr. 2007 Jun;44(6):443-61
pubmed: 17620700
Immunol Res. 2011 May;50(1):1-9
pubmed: 21161695
Crit Care. 2011;15(2):210
pubmed: 21457511
J Pediatr. 1977 Dec;91(6):875-7
pubmed: 925813
Indian J Med Res. 2018 Nov;148(5):511-521
pubmed: 30666978
Am J Trop Med Hyg. 1999 May;60(5):875-8
pubmed: 10344669
Int J Lab Hematol. 2007 Oct;29(5):341-6
pubmed: 17824914
Pediatr Crit Care Med. 2018 Jul;19(7):e367-e373
pubmed: 29782390
Indian J Pathol Microbiol. 2008 Jan-Mar;51(1):102-4
pubmed: 18417876
Crit Care. 2004 Oct;8(5):356-62
pubmed: 15469598
Am J Clin Nutr. 2000 Nov;72(5):1191-5
pubmed: 11063448
Br J Haematol. 1990 Aug;75(4):615-6
pubmed: 2207012
Nutrients. 2018 Oct 17;10(10):
pubmed: 30336639
Lancet. 2013 Jul 6;382(9886):29-40
pubmed: 23602230
Lancet. 2016 Feb 27;387(10021):907-16
pubmed: 26314490
Ann Gastroenterol. 2011;24(2):108-114
pubmed: 24713758
Ann Clin Biochem. 2002 May;39(Pt 3):221-30
pubmed: 12038596
Am J Hematol. 2011 Nov;86(11):923-7
pubmed: 21812017
Ann Clin Lab Sci. 2015 Summer;45(4):396-402
pubmed: 26275690
Crit Care. 2016 Sep 29;20(1):306
pubmed: 27681259
PLoS Med. 2011 Nov;8(11):e1001125
pubmed: 22131908
Blood. 1990 May 1;75(9):1870-6
pubmed: 2331526
Trans R Soc Trop Med Hyg. 2000 May-Jun;94(3):295-8
pubmed: 10975004
Lancet. 2006 Jan 14;367(9505):133-43
pubmed: 16413877
BMC Bioinformatics. 2011 Mar 17;12:77
pubmed: 21414208
Dig Liver Dis. 2019 Mar;51(3):352-357
pubmed: 30538074
Pediatr Crit Care Med. 2005 Jan;6(1):2-8
pubmed: 15636651
Pediatr Crit Care Med. 2018 Jul;19(7):692-693
pubmed: 29985297
Biochem J. 1993 Nov 15;296 ( Pt 1):175-81
pubmed: 8250840
N Engl J Med. 1982 Jun 24;306(25):1520-8
pubmed: 7043270
Blood. 1997 Feb 1;89(3):1052-7
pubmed: 9028338
Crit Care Med. 2016 Jun;44(6):1049-58
pubmed: 26934143

Auteurs

Arun K Baranwal (AK)

Division of Pediatric Critical Care, Advanced Pediatrics Center, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Reena Das (R)

Department of Hematology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Ramachandran Rameshkumar (R)

Division of Pediatric Critical Care, Department of Pediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, 605006 India.

Praveen Kumar-M (P)

Department of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Prateek Bhatia (P)

Advanced Pediatrics Center, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Ashwini Nair (A)

Advanced Pediatrics Center, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Classifications MeSH