Methods to measure calcitonin receptor activity, up-regulated in cell stress, apoptosis and autophagy.

Animals Apoptosis Autophagy Lysosomes Receptors, Calcitonin Signal Transduction
antibody antibody conjugate apoptosis autophagy calcitonin receptor isoform cell stress high content screening nanopore sequencing quantitative PCR

Journal

F1000Research
ISSN: 2046-1402
Titre abrégé: F1000Res
Pays: England
ID NLM: 101594320

Informations de publication

Date de publication:
2021
Historique:
accepted: 02 09 2021
entrez: 8 11 2021
pubmed: 9 11 2021
medline: 16 11 2021
Statut: epublish

Résumé

The expression of the calcitonin receptor (CT Receptor) is widespread throughout the life cycle of mammals and in many diseases, and in these contexts the functions of the common isoforms is largely unknown. The relatively recent development of anti-CT Receptor antibodies that bind separate epitopes on the CT

Identifiants

DOI: 10.12688/f1000research.72845.1 PMID: 34745567 PMC: PMC8543166
pubmed: 34745567
doi: 10.12688/f1000research.72845.1
pmc: PMC8543166
doi:

Substances chimiques

Receptors, Calcitonin 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1019

Informations de copyright

Copyright: © 2021 Wookey P et al.

Déclaration de conflit d'intérêts

Competing interests: PJW holds stock in Apop Biosciences Pty Ltd which owns CalRexinTM. Other authors have no competing interests to disclose.

Références

Cell Death Discov. 2016 Oct 10;2:16062
pubmed: 27777788
Autophagy. 2018;14(8):1435-1455
pubmed: 29940786
Mol Psychiatry. 2020 Jan;25(1):37-47
pubmed: 31695164
Nature. 1978 Nov 16;276(5685):269-70
pubmed: 714156

Auteurs

Peter Wookey (P)

Medicine, University of Melbourne, Heidelberg, Victoria, 3084, Australia.
ORCID: 0000-0002-3937-1621

Pragya Gupta (P)

Medicine, University of Melbourne, Heidelberg, Victoria, 3084, Australia.
ORCID: 0000-0001-8617-0817

Lucas Bittencourt (L)

Medicine, University of Melbourne, Heidelberg, Victoria, 3084, Australia.

Shane Cheung (S)

BOMP, University of Melbourne, Parkville, Victoria, 3052, Australia.

David Hare (D)

Medicine, University of Melbourne, Heidelberg, Victoria, 3084, Australia.

Sebastian Furness (S)

Drug Discovery Biology and Department of Pharmacology, Monash University, Parkville, Victoria, 3052, Australia.
School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, St Lucia, Queensland, 4067, Australia.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Methods to measure calcitonin receptor...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Mort cellulaire › Mort cellulaire régulée › Apoptose › Methods to measure calcitonin receptor...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Autophagie › Methods to measure calcitonin receptor...
questionsmedicales.fr › Cellules › Structures cellulaires › Espace intracellulaire › Cytoplasme › Structures cytoplasmiques › Organites › Vésicules cytoplasmiques › Lysosomes › Methods to measure calcitonin receptor...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs peptidiques › Récepteurs à la calcitonine › Methods to measure calcitonin receptor...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Transduction du signal › Methods to measure calcitonin receptor...