Implications for an imidazol-2-yl carbene intermediate in the rhodanase-catalyzed C-S bond formation reaction of anaerobic ergothioneine biosynthesis.

QM/MM calculation anaerobic biosynthesis carbene intermediate ergothioneine selenonine unnatural amino acid (uAA)

Journal

ACS catalysis
ISSN: 2155-5435
Titre abrégé: ACS Catal
Pays: United States
ID NLM: 101562209

Informations de publication

Date de publication:
19 Mar 2021
Historique:
entrez: 8 11 2021
pubmed: 9 11 2021
medline: 9 11 2021
Statut: ppublish

Résumé

In the anaerobic ergothioneine biosynthetic pathway, a rhodanese domain containing enzyme (EanB) activates tne hercynine's sp

Identifiants

pubmed: 34745712
doi: 10.1021/acscatal.0c04886
pmc: PMC8570591
mid: NIHMS1729583
doi:

Types de publication

Journal Article

Langues

eng

Pagination

3319-3334

Subventions

Organisme : NIGMS NIH HHS
ID : R01 GM106443
Pays : United States

Déclaration de conflit d'intérêts

The authors declare no competing financial interest.

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Auteurs

Ronghai Cheng (R)

Department of Chemistry, Boston University, Boston, MA 02215, USA.

Rui Lai (R)

Department of Chemistry, Boston University, Boston, MA 02215, USA.

Chao Peng (C)

National Facility for Protein Science in Shanghai, Zhangjiang Lab, Shanghai Advanced Research Institute, Chinese Academy of Science, Shanghai 201210, China.

Juan Lopez (J)

Department of Chemistry, Boston University, Boston, MA 02215, USA.

Zhihong Li (Z)

National Facility for Protein Science in Shanghai, Zhangjiang Lab, Shanghai Advanced Research Institute, Chinese Academy of Science, Shanghai 201210, China.

Nathchar Naowarojna (N)

Department of Chemistry, Boston University, Boston, MA 02215, USA.

Kelin Li (K)

Department of Chemistry, Boston University, Boston, MA 02215, USA.

Christina Wong (C)

Department of Chemistry, Boston University, Boston, MA 02215, USA.

Norman Lee (N)

Department of Chemistry, Boston University, Boston, MA 02215, USA.

Stephen A Whelan (SA)

Department of Chemistry, Boston University, Boston, MA 02215, USA.

Lu Qiao (L)

Department of Chemistry, Boston University, Boston, MA 02215, USA.

Mark W Grinstaff (MW)

Department of Chemistry, Boston University, Boston, MA 02215, USA; Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA. 0000-0002-5453-3668.

Jiangyun Wang (J)

Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, People's Republic of China.

Qiang Cui (Q)

Department of Chemistry, Boston University, Boston, MA 02215, USA.

Pinghua Liu (P)

Department of Chemistry, Boston University, Boston, MA 02215, USA.

Classifications MeSH