Bayesian deep learning for reliable oral cancer image classification.
Journal
Biomedical optics express
ISSN: 2156-7085
Titre abrégé: Biomed Opt Express
Pays: United States
ID NLM: 101540630
Informations de publication
Date de publication:
01 Oct 2021
01 Oct 2021
Historique:
received:
31
05
2021
revised:
29
08
2021
accepted:
07
09
2021
entrez:
8
11
2021
pubmed:
9
11
2021
medline:
9
11
2021
Statut:
epublish
Résumé
In medical imaging, deep learning-based solutions have achieved state-of-the-art performance. However, reliability restricts the integration of deep learning into practical medical workflows since conventional deep learning frameworks cannot quantitatively assess model uncertainty. In this work, we propose to address this shortcoming by utilizing a Bayesian deep network capable of estimating uncertainty to assess oral cancer image classification reliability. We evaluate the model using a large intraoral cheek mucosa image dataset captured using our customized device from high-risk population to show that meaningful uncertainty information can be produced. In addition, our experiments show improved accuracy by uncertainty-informed referral. The accuracy of retained data reaches roughly 90% when referring either 10% of all cases or referring cases whose uncertainty value is greater than 0.3. The performance can be further improved by referring more patients. The experiments show the model is capable of identifying difficult cases needing further inspection.
Identifiants
pubmed: 34745746
doi: 10.1364/BOE.432365
pii: 432365
pmc: PMC8547976
doi:
Types de publication
Journal Article
Langues
eng
Pagination
6422-6430Subventions
Organisme : NIDCR NIH HHS
ID : R01 DE030682
Pays : United States
Organisme : NIBIB NIH HHS
ID : UH2 EB022623
Pays : United States
Organisme : NCI NIH HHS
ID : UH3 CA239682
Pays : United States
Informations de copyright
© 2021 Optical Society of America under the terms of the OSA Open Access Publishing Agreement.
Déclaration de conflit d'intérêts
The authors declare that there are no conflicts of interest related to this article.
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