Guar (Cyamopsis tetragonoloba L.) plant gum: From biological applications to advanced nanomedicine.


Journal

International journal of biological macromolecules
ISSN: 1879-0003
Titre abrégé: Int J Biol Macromol
Pays: Netherlands
ID NLM: 7909578

Informations de publication

Date de publication:
15 Dec 2021
Historique:
received: 22 08 2021
revised: 01 11 2021
accepted: 03 11 2021
pubmed: 9 11 2021
medline: 24 12 2021
entrez: 8 11 2021
Statut: ppublish

Résumé

Natural polymers are an efficient class of eco-friendly and biodegradable polymers, because they are readily available, come from natural sources, inexpensive and can be chemically modified with the correct reagents. Guar gum (GG) is a natural polymer with great potential to be used in pharmaceutical formulations due to its unique composition and lack of toxicity. GG can be designed to suit the needs of the biological and medical engineering sectors. In the development of innovative drug delivery systems, GG is commonly utilized as a rate-controlling excipient. In this review, different properties of GG including chemical composition, extraction methods and its usefulness in diabetes, cholesterol lowering, weight control, tablet formulations as well as its food application were discussed. The other purpose of this study is to evaluate potential use of GG and its derivatives for advanced nanomedicine such as drug delivery, tissue engineering and nanosensing. It should be noted that some applicable patents in medical area have also been included in the rest of this survey to extend knowledge about guar gum and its polymeric nature.

Identifiants

pubmed: 34748787
pii: S0141-8130(21)02426-0
doi: 10.1016/j.ijbiomac.2021.11.028
pii:
doi:

Substances chimiques

Galactans 0
Mannans 0
Plant Gums 0
guar gum E89I1637KE

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1972-1985

Informations de copyright

Copyright © 2021 Elsevier B.V. All rights reserved.

Auteurs

Maryam Dehghani Soltani (M)

Department of Chemistry, Yazd University, Yazd 8915818411, Iran.

Heidar Meftahizadeh (H)

Department of Horticultural Sciences, Faculty of Agriculture & Natural Resources, Ardakan University, P.O. Box 184, Ardakan, Iran. Electronic address: hmeftahizade@ardakan.ac.ir.

Mahmood Barani (M)

Medical Mycology and Bacteriology Research Center, Kerman University of Medical Sciences, Kerman 7616913555, Iran.

Abbas Rahdar (A)

Department of Physics, University of Zabol, Zabol, P. O. Box. 98613-35856, Iran.

Seyedeh Maryam Hosseinikhah (SM)

Nanotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.

Mehrnaz Hatami (M)

Department of Medicinal Plants, Faculty of Agriculture and Natural Resources, Arak University, Arak 38156-8-8349, Iran.

Mansour Ghorbanpour (M)

Department of Medicinal Plants, Faculty of Agriculture and Natural Resources, Arak University, Arak 38156-8-8349, Iran. Electronic address: m-ghorbanpour@araku.ac.ir.

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Classifications MeSH