A comprehensive review on endemic and experimental fluorosis in sheep: Its diverse effects and prevention.
Animal Feed
Animals
Antioxidants
/ administration & dosage
Bone Diseases
/ chemically induced
Dietary Supplements
Endemic Diseases
/ prevention & control
Fluorine
/ toxicity
Fluorosis, Dental
/ diagnosis
Minerals
/ administration & dosage
Protective Factors
Risk Assessment
Risk Factors
Sheep
Sheep Diseases
/ chemically induced
Fluoride
Prevention
Sheep
Toxicity
Types of fluorosis
Journal
Toxicology
ISSN: 1879-3185
Titre abrégé: Toxicology
Pays: Ireland
ID NLM: 0361055
Informations de publication
Date de publication:
15 01 2022
15 01 2022
Historique:
received:
16
08
2021
revised:
24
09
2021
accepted:
01
11
2021
pubmed:
9
11
2021
medline:
22
2
2022
entrez:
8
11
2021
Statut:
ppublish
Résumé
Fluoride is a natural element widely distributed in the environment and plays an important role in the growth of humans and animals. However, in many species, high concentrations of fluoride induce several problems, such as dental, skeletal, and non-skeletal fluorosis. Sheep living in endemic areas are sensitive to the chronic toxicity of fluoride, and they have been found to suffer not only from teeth and bone problems but also from other organs. Studies indicating the chronic harmful effects of fluoride on teeth, bones, blood biochemical parameters, kidney, liver, heart, reproductive system and growth in sheep have been clearly summarized in this review. Besides, this work also includes updated progress in terms of prevention or reduction of fluoride toxicity in this species.
Identifiants
pubmed: 34748892
pii: S0300-483X(21)00347-4
doi: 10.1016/j.tox.2021.153025
pii:
doi:
Substances chimiques
Antioxidants
0
Minerals
0
Fluorine
284SYP0193
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
153025Informations de copyright
Copyright © 2021 Elsevier B.V. All rights reserved.