Disseminated tuberculosis with myelofibrosis presentation: a case report.


Journal

Journal of medical case reports
ISSN: 1752-1947
Titre abrégé: J Med Case Rep
Pays: England
ID NLM: 101293382

Informations de publication

Date de publication:
08 Nov 2021
Historique:
received: 06 01 2021
accepted: 24 06 2021
entrez: 9 11 2021
pubmed: 10 11 2021
medline: 11 11 2021
Statut: epublish

Résumé

Primary myelofibrosis is a rare myeloproliferative disorder in middle-aged and old adults and should be distinguished from secondary and reactive causes of bone marrow fibrosis because, in reactive fibrosis, treatment approaches depend on the underlying etiology. Here we report the case of a middle-aged Iranian man who was diagnosed and treated as primary myelofibrosis at presentation, and whose final diagnosis was disseminated tuberculosis with reactive bone marrow fibrosis. It is prudent to evaluate the potential causes of myelofibrosis in any patient with the diagnosis primary myelofibrosis. Tuberculosis can be an important etiology of bone marrow fibrosis, especially in endemic areas.

Sections du résumé

BACKGROUND BACKGROUND
Primary myelofibrosis is a rare myeloproliferative disorder in middle-aged and old adults and should be distinguished from secondary and reactive causes of bone marrow fibrosis because, in reactive fibrosis, treatment approaches depend on the underlying etiology.
CASE PRESENTATION METHODS
Here we report the case of a middle-aged Iranian man who was diagnosed and treated as primary myelofibrosis at presentation, and whose final diagnosis was disseminated tuberculosis with reactive bone marrow fibrosis.
CONCLUSIONS CONCLUSIONS
It is prudent to evaluate the potential causes of myelofibrosis in any patient with the diagnosis primary myelofibrosis. Tuberculosis can be an important etiology of bone marrow fibrosis, especially in endemic areas.

Identifiants

pubmed: 34749829
doi: 10.1186/s13256-021-03038-3
pii: 10.1186/s13256-021-03038-3
pmc: PMC8573919
doi:

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

550

Informations de copyright

© 2021. The Author(s).

Références

Clin Infect Dis. 2002 Jun 15;34(12):1641-3
pubmed: 12032901
Tuberculosis (Edinb). 2016 Mar;97:172-80
pubmed: 26586648
BMJ Case Rep. 2016 Dec 23;2016:
pubmed: 28011890
Int J Mycobacteriol. 2020 Apr-Jun;9(2):216-219
pubmed: 32474548

Auteurs

Mahdi Khatuni (M)

Shahid Beheshti University of Medical Science, Tehran, Iran.

Marziyeh Ghalamkari (M)

Iran University of Medical Science, Tehran, Iran. dr.ghalam@yahoo.com.

Fereshteh Ameli (F)

Tehran University of Medical Science, Tehran, Iran.

Habibeh Yekehtaz (H)

Emory University, Atlanta, Georgia.

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Classifications MeSH