The Manual Therapy and Strengthening for the Hip (MASH) Trial: Protocol for a Multisite Randomized Trial of a Subgroup of Older Adults With Chronic Back and Hip Pain.
Hip Pain
Low Back Pain
Older Adults
Osteoarthritis
Physical Function
Journal
Physical therapy
ISSN: 1538-6724
Titre abrégé: Phys Ther
Pays: United States
ID NLM: 0022623
Informations de publication
Date de publication:
01 01 2022
01 01 2022
Historique:
received:
15
04
2021
revised:
14
08
2021
accepted:
11
10
2021
pubmed:
10
11
2021
medline:
16
2
2022
entrez:
9
11
2021
Statut:
ppublish
Résumé
Chronic low back pain (CLBP) is a disabling and costly condition for older adults that is difficult to properly classify and treat. In a cohort study, a subgroup of older adults with CLBP who had elevated hip pain and hip muscle weakness was identified; this subgroup differentiated itself by being at higher risk for future mobility decline. The primary purpose of this clinical trial is to evaluate whether a hip-focused low back pain (LBP) treatment provides better disability and physical performance outcomes for this at-risk group compared with a spine-focused LBP treatment. This study is a multisite, single-blinded, randomized controlled, parallel arm, Phase II trial conducted across 3 clinical research sites. A total of 180 people aged between 60 and 85 years with CLBP and hip pain are being recruited. Participants undergo a comprehensive baseline assessment and are randomized into 1 of 2 intervention arms: hip-focused or spine-focused. They are treated twice weekly by a licensed physical therapist for 8 weeks and undergo follow-up assessments at 8 weeks and 6 months after randomization. Primary outcome measures include the Quebec Low Back Disability Scale and the 10-Meter Walk Test, which are measures of self-report and performance-based physical function, respectively. This multicenter, randomized clinical trial will determine whether a hip-focused or spine-focused physical therapist intervention results in improved disability and physical performance for a subgroup of older adults with CLBP and hip pain who are at increased risk of mobility decline. This trial will help further the development of effective interventions for this subgroup of older adults with CLBP.
Identifiants
pubmed: 34751784
pii: 6420898
doi: 10.1093/ptj/pzab255
pmc: PMC8831280
pii:
doi:
Banques de données
ClinicalTrials.gov
['NCT04009837']
Types de publication
Clinical Trial, Phase II
Journal Article
Multicenter Study
Randomized Controlled Trial
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NIA NIH HHS
ID : R01 AG041202
Pays : United States
Informations de copyright
© The Author(s) 2022. Published by Oxford University Press on behalf of the American Physical Therapy Association. All rights reserved. For permissions, please email: journals.permissions@oup.com.
Références
N Engl J Med. 2015 Feb 26;372(9):793-5
pubmed: 25635347
Acta Orthop Belg. 2015 Sep;81(3):435-41
pubmed: 26435238
Pain. 1987 Jul;30(1):115-126
pubmed: 3614975
Phys Ther. 2021 Dec 1;101(12):
pubmed: 34636887
Ann Intern Med. 2013 Feb 5;158(3):200-7
pubmed: 23295957
J Gerontol A Biol Sci Med Sci. 2014 Jun;69(6):640-9
pubmed: 24249734
J Gerontol A Biol Sci Med Sci. 2000 Apr;55(4):M221-31
pubmed: 10811152
Qual Life Res. 2010 Sep;19(7):1035-44
pubmed: 20419503
J Am Geriatr Soc. 2015 Mar;63(3):524-30
pubmed: 25754841
Pain. 2013 Dec;154(12):2649-2657
pubmed: 24287107
J Clin Epidemiol. 2013 Sep;66(9):1022-8
pubmed: 23790725
J Gerontol A Biol Sci Med Sci. 2005 Jun;60(6):793-7
pubmed: 15983185
J Gerontol A Biol Sci Med Sci. 1999 Oct;54(10):M487-93
pubmed: 10568530
J Gerontol A Biol Sci Med Sci. 2005 Nov;60(11):1420-4
pubmed: 16339328
Spine (Phila Pa 1976). 1995 May 1;20(9):1017-28
pubmed: 7631231
J Orthop Sports Phys Ther. 2006 Aug;36(8):588-99
pubmed: 16915980
Pain. 2010 Jul;150(1):173-182
pubmed: 20554116
J Orthop Sports Phys Ther. 2012 Apr;42(4):A1-57
pubmed: 22466247
J Orthop Sports Phys Ther. 2012 Jan;42(1):22-9
pubmed: 22027216
Arch Phys Med Rehabil. 2008 Jun;89(6):1146-54
pubmed: 18503813
Arthritis Care Res (Hoboken). 2014 Aug;66(8):1220-6
pubmed: 24339263
JAMA. 2020 Jun 2;323(21):2135-2136
pubmed: 32211830
Cochrane Database Syst Rev. 2016 Jan 13;(1):CD011145
pubmed: 26760674
Eval Health Prof. 2016 Jun;39(2):204-14
pubmed: 24686745
J Geriatr Phys Ther. 2013 Jan-Mar;36(1):24-30
pubmed: 22415358
J Pain. 2014 Jun;15(6):569-85
pubmed: 24787228
J Gerontol. 1994 Mar;49(2):M85-94
pubmed: 8126356
Arch Phys Med Rehabil. 1999 Jul;80(7):837-41
pubmed: 10414771
J Gerontol A Biol Sci Med Sci. 2004 Oct;59(10):1056-61
pubmed: 15528778
J Clin Epidemiol. 2010 Nov;63(11):1179-94
pubmed: 20685078
Arch Phys Med Rehabil. 2018 Jul;99(7):1273-1278
pubmed: 29111171
Arthritis Rheum. 2004 Oct 15;51(5):722-9
pubmed: 15478147
Med Care. 2004 Dec;42(12):1194-201
pubmed: 15550799
Scand J Med Sci Sports. 2010 Jun;20(3):493-501
pubmed: 19558384
Spine J. 2018 Sep;18(9):1540-1551
pubmed: 29391206
J Orthop Sports Phys Ther. 2010 Apr;40(4):197-205
pubmed: 20357418
JAMA. 2011 Jan 5;305(1):50-8
pubmed: 21205966
J Am Geriatr Soc. 2003 Mar;51(3):314-22
pubmed: 12588574
Rheumatology (Oxford). 2011 Sep;50(9):1645-53
pubmed: 21606130
Spine (Phila Pa 1976). 2006 Mar 15;31(6):623-31
pubmed: 16540864
J Stat Softw. 2013 Sep;54(10):
pubmed: 24403868
BMC Musculoskelet Disord. 2003 May 30;4:10
pubmed: 12777182
Am J Public Health. 1983 Apr;73(4):389-95
pubmed: 6219588
Br J Health Psychol. 2019 Sep;24(3):485-496
pubmed: 30955252
Phys Ther. 2014 Jun;94(6):866-74
pubmed: 24557649
Pain. 2019 Apr;160(4):757-761
pubmed: 30371555
J Pain. 2007 Aug;8(8):650-6
pubmed: 17553750
Clin J Pain. 2007 Nov-Dec;23(9):760-6
pubmed: 18075402
JAMA. 2018 Oct 16;320(15):1535-1536
pubmed: 30326521
Spine (Phila Pa 1976). 1995 Jan 1;20(1):11-9
pubmed: 7709270
Clin J Pain. 2016 Oct;32(10):898-906
pubmed: 26736024
Lancet. 2020 Aug 22;396(10250):523-524
pubmed: 32828180
Ann Intern Med. 2004 Dec 21;141(12):920-8
pubmed: 15611489
Clin Rehabil. 2006 Apr;20(4):357-66
pubmed: 16719034
J Gerontol A Biol Sci Med Sci. 2005 Jul;60(7):882-7
pubmed: 16079212
Spine (Phila Pa 1976). 2004 Dec 1;29(23):2593-602
pubmed: 15564907
J Gen Intern Med. 2001 Sep;16(9):606-13
pubmed: 11556941
Spine (Phila Pa 1976). 2003 Jul 1;28(13):1363-71; discussion 1372
pubmed: 12838091
Spine (Phila Pa 1976). 1999 Sep 1;24(17):1813-9
pubmed: 10488512
Arch Phys Med Rehabil. 2008 Nov;89(11):2146-55
pubmed: 18996244
N Engl J Med. 1995 Mar 2;332(9):556-61
pubmed: 7838189
J Clin Epidemiol. 1996 Oct;49(10):1103-10
pubmed: 8826989