Diffusely abnormal white matter in multiple sclerosis.


Journal

Journal of neuroimaging : official journal of the American Society of Neuroimaging
ISSN: 1552-6569
Titre abrégé: J Neuroimaging
Pays: United States
ID NLM: 9102705

Informations de publication

Date de publication:
01 2022
Historique:
revised: 17 10 2021
received: 08 10 2021
accepted: 18 10 2021
pubmed: 10 11 2021
medline: 19 3 2022
entrez: 9 11 2021
Statut: ppublish

Résumé

MRI enables detailed in vivo depiction of multiple sclerosis (MS) pathology. Localized areas of MS damage, commonly referred to as lesions, or plaques, have been a focus of clinical and research MRI studies for over four decades. A nonplaque MRI abnormality which is present in at least 25% of MS patients but has received far less attention is diffusely abnormal white matter (DAWM). DAWM has poorly defined boundaries and a signal intensity that is between normal-appearing white matter and classic lesions on proton density and T

Identifiants

pubmed: 34752664
doi: 10.1111/jon.12945
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

5-16

Informations de copyright

© 2021 American Society of Neuroimaging.

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Auteurs

James Cairns (J)

Department of Medicine (Neurology), University of British Columbia, British Columbia, Vancouver, Canada.
Department of Radiology, University of British Columbia, British Columbia, Vancouver, Canada.

Irene M Vavasour (IM)

Department of Radiology, University of British Columbia, British Columbia, Vancouver, Canada.
International Collaboration on Repair Discoveries, Blusson Spinal Cord Centre, University of British Columbia, British Columbia, Vancouver, Canada.

Anthony Traboulsee (A)

Department of Medicine (Neurology), University of British Columbia, British Columbia, Vancouver, Canada.

Robert Carruthers (R)

Department of Medicine (Neurology), University of British Columbia, British Columbia, Vancouver, Canada.

Shannon H Kolind (SH)

Department of Medicine (Neurology), University of British Columbia, British Columbia, Vancouver, Canada.
Department of Radiology, University of British Columbia, British Columbia, Vancouver, Canada.
International Collaboration on Repair Discoveries, Blusson Spinal Cord Centre, University of British Columbia, British Columbia, Vancouver, Canada.
Department of Physics & Astronomy, University of British Columbia, British Columbia, Vancouver, Canada.

David K B Li (DKB)

Department of Medicine (Neurology), University of British Columbia, British Columbia, Vancouver, Canada.
Department of Radiology, University of British Columbia, British Columbia, Vancouver, Canada.

G R Wayne Moore (GRW)

Department of Medicine (Neurology), University of British Columbia, British Columbia, Vancouver, Canada.
International Collaboration on Repair Discoveries, Blusson Spinal Cord Centre, University of British Columbia, British Columbia, Vancouver, Canada.
Department of Pathology & Laboratory Medicine, University of British Columbia, British Columbia, Vancouver, Canada.

Cornelia Laule (C)

Department of Radiology, University of British Columbia, British Columbia, Vancouver, Canada.
International Collaboration on Repair Discoveries, Blusson Spinal Cord Centre, University of British Columbia, British Columbia, Vancouver, Canada.
Department of Physics & Astronomy, University of British Columbia, British Columbia, Vancouver, Canada.
Department of Pathology & Laboratory Medicine, University of British Columbia, British Columbia, Vancouver, Canada.

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