Idiopathic portal vein thrombosis not related to hepatic disease or malignancy.
cirrhosis
haematology (incl blood transfusion)
portal vein
venous thromboembolism
Journal
BMJ case reports
ISSN: 1757-790X
Titre abrégé: BMJ Case Rep
Pays: England
ID NLM: 101526291
Informations de publication
Date de publication:
09 Nov 2021
09 Nov 2021
Historique:
entrez:
10
11
2021
pubmed:
11
11
2021
medline:
12
11
2021
Statut:
epublish
Résumé
Acute portal vein thrombosis (PVT) is a rare disorder defined by the sudden occlusion of the portal vein, which could be partial or complete. Prothrombotic states, inherited or acquired, are thought to be the cause in patients without cirrhosis or malignancy. However, the aetiology of some cases remains idiopathic despite a multidisciplinary diagnostic approach. The initial diagnostic modality to confirm PVT is either contrast-enhanced abdominal (CT) or MRI; as it can identify predisposing factors, and detect evidence of complications. Eliciting the underlying aetiology is critical to guide overall management and prevent future recurrence. The purpose of treatment is to stop thrombus extension and achieve portal vein patency by anticoagulation to optimise outcomes. Herein, we present an unusual case of spontaneous PVT in a young woman. We will also discuss the evaluation of patients without obvious aetiology.
Identifiants
pubmed: 34753728
pii: 14/11/e245620
doi: 10.1136/bcr-2021-245620
pmc: PMC8578946
pii:
doi:
Substances chimiques
Anticoagulants
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Informations de copyright
© BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
Références
Blood Adv. 2020 Feb 25;4(4):655-666
pubmed: 32078681
Gastrointest Radiol. 1992 Spring;17(2):135-40
pubmed: 1551509
Aliment Pharmacol Ther. 2010 Nov;32(9):1154-62
pubmed: 21039677
World J Gastroenterol. 2006 Apr 7;12(13):2115-9
pubmed: 16610067
Clin Gastroenterol Hepatol. 2008 Dec;6(12):1412-7
pubmed: 19081529
Hepatology. 2000 Feb;31(2):345-8
pubmed: 10655256
Aliment Pharmacol Ther. 2015 Feb;41(3):276-92
pubmed: 25475582
Surg Laparosc Endosc Percutan Tech. 2006 Feb;16(1):4-7
pubmed: 16552370
Eur J Cancer. 2012 Mar;48(4):586-93
pubmed: 22129887
Adv Exp Med Biol. 2017;906:229-239
pubmed: 27638623
Hepatology. 2005 Mar;41(3):603-8
pubmed: 15726653
J Hepatol. 2016 Feb;64(2):427-432
pubmed: 26334577
Surg Endosc. 2004 Jul;18(7):1140-3
pubmed: 15156376
Gastroenterol Hepatol. 2016 Jun-Jul;39(6):403-10
pubmed: 26547613
Clin Liver Dis (Hoboken). 2014 Jun 25;3(6):118-121
pubmed: 30992903
World J Surg. 2014 Jun;38(6):1491-7
pubmed: 24407940
Hepatology. 2010 Jan;51(1):210-8
pubmed: 19821530
N Engl J Med. 1998 Apr 23;338(17):1169-73
pubmed: 9554856
Am J Gastroenterol. 2007 Nov;102(11):2464-70
pubmed: 17958760
Am J Med. 2007 Jun;120(6):552.e9-11
pubmed: 17524760
J Hepatol. 2004 May;40(5):736-41
pubmed: 15094219
Am J Case Rep. 2015 Sep 17;16:627-30
pubmed: 26378714
Blood. 2014 Dec 11;124(25):3685-91
pubmed: 25320239
Ann Intern Med. 2008 Sep 2;149(5):323-33
pubmed: 18765702
J Clin Transl Hepatol. 2019 Jun 28;7(2):154-164
pubmed: 31293916
Gastroenterology. 1999 Jan;116(1):144-8
pubmed: 9869612
Dig Liver Dis. 2017 Feb;49(2):113-120
pubmed: 27965037
Thromb Haemost. 2008 Apr;99(4):675-82
pubmed: 18392325
Hepatology. 2009 May;49(5):1729-64
pubmed: 19399912
Aliment Pharmacol Ther. 2007 Dec;26 Suppl 2:203-9
pubmed: 18081663
QJM. 2000 Aug;93(8):531-4
pubmed: 10924535