Cardiovascular Morbidity and Mortality in Adult Patients With Repaired Aortic Coarctation.
adult congenital heart disease
aortic coarctation
cardiovascular events
survival
Journal
Journal of the American Heart Association
ISSN: 2047-9980
Titre abrégé: J Am Heart Assoc
Pays: England
ID NLM: 101580524
Informations de publication
Date de publication:
16 11 2021
16 11 2021
Historique:
pubmed:
11
11
2021
medline:
26
2
2022
entrez:
10
11
2021
Statut:
ppublish
Résumé
Background The long-term burden of cardiovascular disease after repair of coarctation of the aorta (CoA) has not been elucidated. We aimed to determine the incidence of and risk factors for cardiovascular events in adult patients with repaired CoA. Additionally, mortality rates were compared between adults with repaired CoA and the general population. Methods and Results Using the Dutch Congenital Corvitia (CONCOR) registry, patients aged ≥16 years with previous surgical or transcatheter CoA repair from 5 tertiary referral centers were included. Cardiovascular events were recorded, comprising coronary artery disease, stroke/transient ischemic attack, aortic complications, arrhythmias, heart failure hospitalizations, endocarditis, and cardiovascular death. In total, 920 patients (median age, 24 years [range 16-74 years]) were included. After a mean follow-up of 9.3±5.1 years, 191 patients (21%) experienced at least 1 cardiovascular event. A total of 270 cardiovascular events occurred, of which aortic complications and arrhythmias were most frequent. Older age at initial CoA repair (hazard ratio [HR], 1.017; 95% CI, 1.000-1.033 [
Identifiants
pubmed: 34755532
doi: 10.1161/JAHA.121.023199
pmc: PMC8751912
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e023199Références
Am J Cardiol. 2011 Aug 1;108(3):435-9
pubmed: 21550580
J Am Soc Echocardiogr. 2015 Jul;28(7):727-54
pubmed: 26140936
Eur Heart J. 2010 May;31(10):1220-9
pubmed: 20207625
JAMA. 2007 Aug 22;298(8):874-9
pubmed: 17712071
Stroke. 2007 Oct;38(10):2681-5
pubmed: 17761929
Hypertension. 2020 Jun;75(6):1334-1357
pubmed: 32370572
World J Cardiol. 2015 Nov 26;7(11):765-75
pubmed: 26635924
Int J Cardiol. 2005 Apr 20;100(2):335-6
pubmed: 15823645
Eur Heart J. 2021 Feb 11;42(6):563-645
pubmed: 32860028
Int J Cardiol. 2017 Feb 1;228:347-351
pubmed: 27866026
Eur Heart J. 2014 Mar;35(11):725-32
pubmed: 23882067
Am J Med. 1995 May;98(5):476-84
pubmed: 7733127
Heart. 2015 Aug;101(15):1190-5
pubmed: 25810155
Heart. 2019 Oct;105(19):1464-1470
pubmed: 31315937
Curr Cardiol Rep. 2004 Mar;6(2):106-11
pubmed: 14759353
Heart. 2019 Aug;105(15):1190-1196
pubmed: 30923175
J Am Coll Cardiol. 2020 Apr 28;75(16):2089-2090
pubmed: 32327108
Circ Cardiovasc Imaging. 2020 Feb;13(2):e009672
pubmed: 32069118
Int J Cardiol. 2005 Mar 18;99(2):295-9
pubmed: 15749190
N Engl J Med. 1990 May 31;322(22):1561-6
pubmed: 2139921
Circulation. 2019 Apr 2;139(14):e698-e800
pubmed: 30586767
Circulation. 2010 Apr 6;121(13):e266-369
pubmed: 20233780
J Am Coll Cardiol. 2013 Sep 10;62(11):1020-5
pubmed: 23850909
Hypertension. 2017 Mar;69(3):501-509
pubmed: 28115510
J Thorac Cardiovasc Surg. 2007 Sep;134(3):738-45
pubmed: 17723827
J Thorac Cardiovasc Surg. 2019 Jan;157(1):213-222
pubmed: 30342758
Am J Cardiol. 2009 Oct 1;104(7):1001-6
pubmed: 19766771
J Am Coll Cardiol. 2016 Apr 26;67(16):1956-64
pubmed: 27102511
Circulation. 2001 Sep 18;104(12 Suppl 1):I165-70
pubmed: 11568050
N Engl J Med. 2003 Jun 12;348(24):2407-15
pubmed: 12802026
J Am Heart Assoc. 2018 Jun 1;7(11):
pubmed: 29858370
Circulation. 2018 Mar 20;137(12):e67-e492
pubmed: 29386200
Am J Cardiol. 2002 Mar 1;89(5):541-7
pubmed: 11867038
Mayo Clin Proc. 2003 Dec;78(12):1491-9
pubmed: 14661678
Circulation. 1989 Oct;80(4):840-5
pubmed: 2791247
Circulation. 2018 Feb 27;137(9):961-972
pubmed: 29483172
Int J Cardiol. 2005 Jun 8;101(3):399-406
pubmed: 15907407