Gonadotropin-inhibitory hormone as a regulator of social interactions in vertebrates.

Animals Gonadotropins / metabolism Hypothalamic Hormones / metabolism Hypothalamus / metabolism Social Interaction Vertebrates / metabolism
Glucocorticoid Gonadotropin-inhibitory hormone Gonadotropin-releasing hormone-I Hypothalamic–pituitary-gonadal axis Noradrenaline RF amide-related peptide Social defeat stress Social environment Social rank Visual cue

Journal

Frontiers in neuroendocrinology
ISSN: 1095-6808
Titre abrégé: Front Neuroendocrinol
Pays: United States
ID NLM: 7513292

Informations de publication

Date de publication:
01 2022
Historique:
received: 22 06 2021
revised: 12 09 2021
accepted: 11 10 2021
pubmed: 11 11 2021
medline: 5 3 2022
entrez: 10 11 2021
Statut: ppublish

Résumé

The social environment changes circulating hormone levels and expression of social behavior in animals. Social information is perceived by sensory systems, leading to cellular and molecular changes through neural processes. Peripheral reproductive hormone levels are regulated by activity in the hypothalamic-pituitary-gonadal (HPG) axis. Until the end of the last century, the neurochemical systems that convey social information to the HPG axis were not well understood. Gonadotropin-inhibitory hormone (GnIH) was the first hypothalamic neuropeptide shown to inhibit gonadotropin release, in 2000. GnIH is now regarded as a negative upstream regulator of the HPG axis, and it is becoming increasingly evident that it responds to social cues. In addition to controlling reproductive physiology, GnIH seems to modulate the reproductive behavior of animals. Here, we review studies investigating how GnIH neurons respond to social information and describe the mechanisms through which GnIH regulates social behavior.

Identifiants

DOI: 10.1016/j.yfrne.2021.100954 PMID: 34757092
pubmed: 34757092
pii: S0091-3022(21)00056-X
doi: 10.1016/j.yfrne.2021.100954
pii:
doi:

Substances chimiques

Gonadotropins 0
Hypothalamic Hormones 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

100954

Subventions

Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/P013759/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/M027805/1
Pays : United Kingdom

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Auteurs

Yasuko Tobari (Y)

Laboratory of Animal Genetics and Breeding, Department of Animal Science and Biotechnology, School of Veterinary Medicine, Azabu University, Fuchinobe 1-17-71, Chuo-ku, Sagamihara City 252-5201, Japan; Center for Human and Animal Symbiosis Science, Azabu University, Fuchinobe 1-17-71, Chuo-ku, Sagamihara, Kanagawa 252-5201, Japan. Electronic address: tobari@azabu-u.ac.jp.

Yana Aleksandrova (Y)

The Roslin Institute and R(D)SVS, The University of Edinburgh, Easter Bush, Midlothian, EH25 9RG, UK.

Yoko Fukahori (Y)

Laboratory of Integrative Brain Sciences, Department of Biology, Waseda University, and Center for Medical Life Science of Waseda University, Tokyo 162-8480, Japan.

Kazuyoshi Tsutsui (K)

Laboratory of Integrative Brain Sciences, Department of Biology, Waseda University, and Center for Medical Life Science of Waseda University, Tokyo 162-8480, Japan; Graduate School of Integrated Sciences for Life, Hiroshima University, Kagamiyama 1-7-1, Higashi-Hiroshima 739-8521, Japan.

Simone L Meddle (SL)

The Roslin Institute and R(D)SVS, The University of Edinburgh, Easter Bush, Midlothian, EH25 9RG, UK.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Gonadotropin-inhibitory hormone as a regulator...
questionsmedicales.fr › Gonadotrophines › Gonadotropin-inhibitory hormone as a regulator...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de tissu nerveux › Neuropeptides › Hormones hypothalamiques › Gonadotropin-inhibitory hormone as a regulator...
questionsmedicales.fr › Système nerveux › Système nerveux central › Encéphale › Prosencéphale › Diencéphale › Hypothalamus › Gonadotropin-inhibitory hormone as a regulator...
questionsmedicales.fr › Comportement et mécanismes comportementaux › Relations interpersonnelles › Interaction sociale › Gonadotropin-inhibitory hormone as a regulator...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Gonadotropin-inhibitory hormone as a regulator...