Understanding stress-induced disorder and breakage in organic crystals: beyond crystal structure anisotropy.


Journal

Chemical science
ISSN: 2041-6520
Titre abrégé: Chem Sci
Pays: England
ID NLM: 101545951

Informations de publication

Date de publication:
03 Nov 2021
Historique:
received: 07 06 2021
accepted: 08 10 2021
entrez: 11 11 2021
pubmed: 12 11 2021
medline: 12 11 2021
Statut: epublish

Résumé

Crystal engineering has advanced the strategies for design and synthesis of organic solids with the main focus being on customising the properties of the materials. Research in this area has a significant impact on large-scale manufacturing, as industrial processes may lead to the deterioration of such properties due to stress-induced transformations and breakage. In this work, we investigate the mechanical properties of structurally related labile multicomponent solids of carbamazepine (CBZ), namely the dihydrate (CBZ·2H

Identifiants

pubmed: 34760213
doi: 10.1039/d1sc03095g
pii: d1sc03095g
pmc: PMC8565387
doi:

Types de publication

Journal Article

Langues

eng

Pagination

14270-14280

Informations de copyright

This journal is © The Royal Society of Chemistry.

Déclaration de conflit d'intérêts

The authors declare there were no conflicts of interest in this work.

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Auteurs

Gabriela Schneider-Rauber (G)

Department of Chemistry, University of Cambridge Cambridge CB2 1EW UK wj10@cam.ac.uk.

Mihails Arhangelskis (M)

Faculty of Chemistry, University of Warsaw 1 Pasteura Street Warsaw 02-093 Poland.

Wei-Pin Goh (WP)

School of Chemical and Process Engineering, University of Leeds Leeds LS2 9JT UK.

James Cattle (J)

School of Chemical and Process Engineering, University of Leeds Leeds LS2 9JT UK.

Nicole Hondow (N)

School of Chemical and Process Engineering, University of Leeds Leeds LS2 9JT UK.

Rik Drummond-Brydson (R)

School of Chemical and Process Engineering, University of Leeds Leeds LS2 9JT UK.

Mojtaba Ghadiri (M)

School of Chemical and Process Engineering, University of Leeds Leeds LS2 9JT UK.

Kushal Sinha (K)

Process Research and Development, AbbVie, Inc. North Chicago IL USA.

Raimundo Ho (R)

Process Research and Development, AbbVie, Inc. North Chicago IL USA.

Nandkishor K Nere (NK)

Process Research and Development, AbbVie, Inc. North Chicago IL USA.

Shailendra Bordawekar (S)

Process Research and Development, AbbVie, Inc. North Chicago IL USA.

Ahmad Y Sheikh (AY)

Process Research and Development, AbbVie, Inc. North Chicago IL USA.

William Jones (W)

Department of Chemistry, University of Cambridge Cambridge CB2 1EW UK wj10@cam.ac.uk.

Classifications MeSH