Early-onset twin-twin transfusion syndrome: Case series and systematic review.

diagnostic imaging criteria fetal therapies multiple pregnancy pregnancy outcome twin–twin transfusion syndrome

Journal

Australasian journal of ultrasound in medicine
ISSN: 1836-6864
Titre abrégé: Australas J Ultrasound Med
Pays: Australia
ID NLM: 101583539

Informations de publication

Date de publication:
Nov 2019
Historique:
entrez: 11 11 2021
pubmed: 30 8 2019
medline: 30 8 2019
Statut: epublish

Résumé

Data on the outcomes of early-onset twin-twin transfusion syndrome (TTTS), diagnosed before 18 weeks gestational age (GA), are sparse. We aimed to review the diagnosis, management and outcomes of early-onset TTTS. Pregnancy records at a single referral unit 2010-6 were reviewed. In early-onset TTTS cases, data for pregnancy characteristics, interventions and outcomes were collected. PubMed and Scopus databases were searched for studies including pregnant women with early-onset TTTS. The primary outcome measure was livebirths. Case series: 58 cases of early-onset TTTS 2010-6, with full outcome data in 44. Diagnostic criteria were variable. Median GA at intervention was 17 In comparison with the commonly accepted overall survival for TTTS treated after 18 weeks of 60-90%, outcomes in early-onset TTTS were at the lower bound of this range. Gestational age at intervention is similar to that of later onset TTTS, indicating a lack of therapeutic options when a diagnosis is made before 18 weeks.

Identifiants

pubmed: 34760571
doi: 10.1002/ajum.12176
pii: AJUM12176
pmc: PMC8411716
doi:

Types de publication

Journal Article

Langues

eng

Pagination

286-294

Informations de copyright

© 2019 Australasian Society for Ultrasound in Medicine.

Déclaration de conflit d'intérêts

The authors declare no competing interests, financial or otherwise.

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Auteurs

Bronacha Mylrea-Foley (B)

Queen Charlotte's and Chelsea Hospital Imperial College Healthcare NHS Trust London UK.

Caroline J Shaw (CJ)

Institute of Reproductive and Developmental Biology Imperial College London London W12 0HS UK.

Nirupama Harikumar (N)

Institute of Reproductive and Developmental Biology Imperial College London London W12 0HS UK.

Sophie Legg (S)

Institute of Reproductive and Developmental Biology Imperial College London London W12 0HS UK.

Shireen Meher (S)

Birmingham Women's and Children's NHS Foundation Trust Birmingham UK.

Christoph C Lees (CC)

Institute of Reproductive and Developmental Biology Imperial College London London W12 0HS UK.
Department of Development & Regeneration KU Leuven Belgium.

Classifications MeSH