Clinical features and mortality in COVID-19 SARI versus non COVID-19 SARI cases from Western Rajasthan, India.

Coronavirus Disease 2019 SARS-CoV2 severe acute respiratory infection

Journal

Journal of family medicine and primary care
ISSN: 2249-4863
Titre abrégé: J Family Med Prim Care
Pays: India
ID NLM: 101610082

Informations de publication

Date de publication:
Sep 2021
Historique:
received: 02 01 2021
revised: 19 06 2021
accepted: 20 06 2021
entrez: 11 11 2021
pubmed: 12 11 2021
medline: 12 11 2021
Statut: ppublish

Résumé

In March 2020, the Indian Council of Medical Research (ICMR) issued guidelines that all patients presenting with severe acute respiratory infections (SARI) should be investigated for coronavirus disease 2019 (COVID-19). Following the same protocol, in our institute, all patients with SARI were transferred to the COVID-19 suspect intensive care unit (ICU) and investigated for COVID-19. This study was planned to examine the demographical, clinical features, and outcomes of the first 500 suspected patients of COVID-19 with SARI admitted in the COVID-19 suspect ICU at a tertiary care center. Between March 7 and July 20, 2020, 500 patients were admitted to the COVID-19 suspect ICU. We analyzed the demographical, clinical features, and outcomes between COVID-19 positive and negative SARI cases. The records of all the patients were reviewed until July 31, 2020. Of the 500 suspected patients admitted to the hospital, 88 patients showed positive results for COVID-19 by reverse transcription-polymerase chain reaction (RT-PCR) of the nasopharyngeal swabs. The mean age in the positive group was higher (55.31 ± 16.16 years) than in the negative group (40.46 ± 17.49 years) ( In the present article, 17.6% of SARI were due to COVID-19 infection with significantly higher mortality (34.1%) in COVID-19 positive patients with SARI. Although all patients presenting as SARI have considerable mortality rates, the COVID-19-associated SARI cases thus had an almost one-third risk of mortality.

Sections du résumé

BACKGROUND BACKGROUND
In March 2020, the Indian Council of Medical Research (ICMR) issued guidelines that all patients presenting with severe acute respiratory infections (SARI) should be investigated for coronavirus disease 2019 (COVID-19). Following the same protocol, in our institute, all patients with SARI were transferred to the COVID-19 suspect intensive care unit (ICU) and investigated for COVID-19.
METHODS METHODS
This study was planned to examine the demographical, clinical features, and outcomes of the first 500 suspected patients of COVID-19 with SARI admitted in the COVID-19 suspect ICU at a tertiary care center. Between March 7 and July 20, 2020, 500 patients were admitted to the COVID-19 suspect ICU. We analyzed the demographical, clinical features, and outcomes between COVID-19 positive and negative SARI cases. The records of all the patients were reviewed until July 31, 2020.
RESULTS RESULTS
Of the 500 suspected patients admitted to the hospital, 88 patients showed positive results for COVID-19 by reverse transcription-polymerase chain reaction (RT-PCR) of the nasopharyngeal swabs. The mean age in the positive group was higher (55.31 ± 16.16 years) than in the negative group (40.46 ± 17.49 years) (
CONCLUSION CONCLUSIONS
In the present article, 17.6% of SARI were due to COVID-19 infection with significantly higher mortality (34.1%) in COVID-19 positive patients with SARI. Although all patients presenting as SARI have considerable mortality rates, the COVID-19-associated SARI cases thus had an almost one-third risk of mortality.

Identifiants

pubmed: 34760737
doi: 10.4103/jfmpc.jfmpc_14_21
pii: JFMPC-10-3240
pmc: PMC8565113
doi:

Types de publication

Journal Article

Langues

eng

Pagination

3240-3246

Informations de copyright

Copyright: © 2021 Journal of Family Medicine and Primary Care.

Déclaration de conflit d'intérêts

There are no conflicts of interest.

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Auteurs

Ankur Sharma (A)

Department of Trauma and Emergency (Anaesthesiology), All India Institute of Medical Sciences (AIIMS), Jodhpur, Rajasthan, India.

Nikhil Kothari (N)

Department of Anaesthesiology and Critical Care, All India Institute of Medical Sciences (AIIMS), Jodhpur, Rajasthan, India.

Akhil Dhanesh Goel (AD)

Department of Community and Family Medicine, All India Institute of Medical Sciences (AIIMS), Jodhpur, Rajasthan, India.

Balakrishnan Narayanan (B)

Department of Anaesthesiology and Critical Care, All India Institute of Medical Sciences (AIIMS), Jodhpur, Rajasthan, India.

Shilpa Goyal (S)

Department of Anaesthesiology and Critical Care, All India Institute of Medical Sciences (AIIMS), Jodhpur, Rajasthan, India.

Pradeep Bhatia (P)

Department of Anaesthesiology and Critical Care, All India Institute of Medical Sciences (AIIMS), Jodhpur, Rajasthan, India.

Deepak Kumar (D)

Department of General Medicine, All India Institute of Medical Sciences (AIIMS), Jodhpur, Rajasthan, India.

Gopal Krishna Bohra (GK)

Department of General Medicine, All India Institute of Medical Sciences (AIIMS), Jodhpur, Rajasthan, India.

Nishant Kumar Chauhan (NK)

Department of Pulmonary Medicine, All India Institute of Medical Sciences (AIIMS), Jodhpur, Rajasthan, India.

Ramniwas Jalandra (R)

Department of Pulmonary Medicine, All India Institute of Medical Sciences (AIIMS), Jodhpur, Rajasthan, India.

Naveen Dutt (N)

Department of Pulmonary Medicine, All India Institute of Medical Sciences (AIIMS), Jodhpur, Rajasthan, India.

Pankaj Bhardwaj (P)

Department of Community and Family Medicine, All India Institute of Medical Sciences (AIIMS), Jodhpur, Rajasthan, India.

Mahendra Kumar Garg (MK)

Department of General Medicine, All India Institute of Medical Sciences (AIIMS), Jodhpur, Rajasthan, India.

Sanjeev Misra (S)

Department of Surgical Oncology, All India Institute of Medical Sciences (AIIMS), Jodhpur, Rajasthan, India.

Classifications MeSH