Management of vasovagal syncope.

Autonomic Faint Management Pharmacotherapy Reflex Syncope Vasovagal

Journal

Autonomic neuroscience : basic & clinical
ISSN: 1872-7484
Titre abrégé: Auton Neurosci
Pays: Netherlands
ID NLM: 100909359

Informations de publication

Date de publication:
12 2021
Historique:
received: 05 07 2021
revised: 27 09 2021
accepted: 01 11 2021
pubmed: 12 11 2021
medline: 15 12 2021
entrez: 11 11 2021
Statut: ppublish

Résumé

Vasovagal syncope (VVS) is a very common form of fainting. Treatment begins with patient education about the mechanism of fainting, and the non-lethal nature of vasovagal syncope. In this article, we review several non-pharmacological approaches that form the foundation of our current treatments. These include increases in dietary salt and water intake, the use of compression garments, physical counter-maneuvers and tilt-training. When these approaches are inadequate, medications can sometimes be effective. While the evidence base for the pharmacological treatment of VVS is modest, recent trial data have found drugs to be useful in placebo-controlled randomized trials. For select patients, and those patients more refractory to medications, procedural treatments may be an option. In this review, we discuss the current state of evidence for the non-pharmacological and pharmacological treatments for VVS, as well as some novel, emerging therapies for VVS.

Identifiants

pubmed: 34763249
pii: S1566-0702(21)00134-X
doi: 10.1016/j.autneu.2021.102904
pii:
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

102904

Subventions

Organisme : CIHR
ID : MOP142426
Pays : Canada
Organisme : NCATS NIH HHS
ID : UL1 TR000445
Pays : United States

Informations de copyright

Copyright © 2021 Elsevier B.V. All rights reserved.

Auteurs

Brennan A Ballantyne (BA)

Department of Cardiac Sciences, Libin Cardiovascular Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.

Sevan Letourneau-Shesaf (S)

Department of Cardiac Sciences, Libin Cardiovascular Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.

Satish R Raj (SR)

Department of Cardiac Sciences, Libin Cardiovascular Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada; Autonomic Dysfunction Center, Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. Electronic address: satish.raj@ucalgary.ca.

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Classifications MeSH