Structure-Activity Relationship of Novel Second-Generation Synthetic Cathinones: Mechanism of Action, Locomotion, Reward, and Immediate-Early Genes.
immediate-early gene (IEG)
new psychoactive substance
psychostimulant
releasers
reward
structure–activity relationship
synthetic cathinones
Journal
Frontiers in pharmacology
ISSN: 1663-9812
Titre abrégé: Front Pharmacol
Pays: Switzerland
ID NLM: 101548923
Informations de publication
Date de publication:
2021
2021
Historique:
received:
29
07
2021
accepted:
23
09
2021
entrez:
12
11
2021
pubmed:
13
11
2021
medline:
13
11
2021
Statut:
epublish
Résumé
Several new synthetic cathinones, which mimic the effect of classical psychostimulants such as cocaine or MDMA, have appeared in the global illicit drug market in the last decades. In fact, the illicit drug market is continually evolving by constantly adding small modifications to the common chemical structure of synthetic cathinones. Thus, the aim of this study was to investigate the
Identifiants
pubmed: 34764870
doi: 10.3389/fphar.2021.749429
pii: 749429
pmc: PMC8576102
doi:
Types de publication
Journal Article
Langues
eng
Pagination
749429Informations de copyright
Copyright © 2021 Nadal-Gratacós, Alberto-Silva, Rodríguez-Soler, Urquizu, Espinosa-Velasco, Jäntsch, Holy, Batllori, Berzosa, Pubill, Camarasa, Sitte, Escubedo and López-Arnau.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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