Validation of a Brief Computerized Cognitive Assessment in Multiple Sclerosis (BCCAMS) and comparison with reference batteries.


Journal

Multiple sclerosis (Houndmills, Basingstoke, England)
ISSN: 1477-0970
Titre abrégé: Mult Scler
Pays: England
ID NLM: 9509185

Informations de publication

Date de publication:
06 2022
Historique:
pubmed: 13 11 2021
medline: 26 5 2022
entrez: 12 11 2021
Statut: ppublish

Résumé

The Brief Computerized Cognitive Assessment in Multiple Sclerosis (BCCAMS) is a short neuropsychological battery for persons with multiple sclerosis (PwMS). The main objective of the study is to validate the BCCAMS. PwMS and healthy subjects (HS) were evaluated using the BCCAMS which include two computerized tests, the Computerized Speed Cognitive Test and the Computerized Episodic Visual Memory Test (CEVMT), a newly developed visuospatial memory test, and the French learning test. The Minimal Assessment of Cognitive Function in MS (MACFIMS), including the Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) tests, was also administered. Regression-based norms of the BCCAMS were calculated in 276 HS. BCCAMS was compared with BICAMS and MACFIMS for detection of cognitive impairment (CI). Out of 120 PwMS, CI was detected using the BCCAMS, BICAMS (one impaired test), and MACFIMS (two impaired tests) in 59.1%, 50%, and 37.9%, respectively. The BCCAMS produced the same predictive value as that of the BICAMS battery for detecting CI in the MACFIMS. This study validated the BCCAMS as a validated computerized short assessment for information processing speed and learning in MS.

Sections du résumé

BACKGROUND
The Brief Computerized Cognitive Assessment in Multiple Sclerosis (BCCAMS) is a short neuropsychological battery for persons with multiple sclerosis (PwMS).
OBJECTIVES
The main objective of the study is to validate the BCCAMS.
METHODS
PwMS and healthy subjects (HS) were evaluated using the BCCAMS which include two computerized tests, the Computerized Speed Cognitive Test and the Computerized Episodic Visual Memory Test (CEVMT), a newly developed visuospatial memory test, and the French learning test. The Minimal Assessment of Cognitive Function in MS (MACFIMS), including the Brief International Cognitive Assessment for Multiple Sclerosis (BICAMS) tests, was also administered. Regression-based norms of the BCCAMS were calculated in 276 HS. BCCAMS was compared with BICAMS and MACFIMS for detection of cognitive impairment (CI).
RESULTS
Out of 120 PwMS, CI was detected using the BCCAMS, BICAMS (one impaired test), and MACFIMS (two impaired tests) in 59.1%, 50%, and 37.9%, respectively. The BCCAMS produced the same predictive value as that of the BICAMS battery for detecting CI in the MACFIMS.
CONCLUSION
This study validated the BCCAMS as a validated computerized short assessment for information processing speed and learning in MS.

Identifiants

pubmed: 34766866
doi: 10.1177/13524585211054006
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1112-1120

Auteurs

Nicolas Maubeuge (N)

Univ. Poitiers, Poitiers France.

Mathilde Sa Deloire (MS)

CHU de Bordeaux, Bordeaux, France.

Bruno Brochet (B)

INSERM U1215, Neurocentre Magendie, Université de Bordeaux, Bordeaux, France/Univ. Bordeaux, Bordeaux, France.

Julie Charré-Morin (J)

CHU de Bordeaux, Bordeaux, France.

Aurore Saubusse (A)

CHU de Bordeaux, Bordeaux, France.

Aurélie Ruet (A)

CHU de Bordeaux, Bordeaux, France/INSERM U1215, Neurocentre Magendie, Bordeaux, France/Univ. Bordeaux, Bordeaux, France.

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