Long working hours and risk of cardiovascular outcomes and diabetes type II: five-year follow-up of the Gutenberg Health Study (GHS).
Arterial stiffness
Diabetes
Occupational health
Prospective cohort study; cardiovascular disease
Working time
Journal
International archives of occupational and environmental health
ISSN: 1432-1246
Titre abrégé: Int Arch Occup Environ Health
Pays: Germany
ID NLM: 7512134
Informations de publication
Date de publication:
Jan 2022
Jan 2022
Historique:
received:
29
01
2021
accepted:
24
05
2021
pubmed:
13
11
2021
medline:
5
4
2022
entrez:
12
11
2021
Statut:
ppublish
Résumé
The aims of this study were to determine if there was an increased risk of incident cardiovascular disease (CVD) and diabetes and an increase in arterial stiffness in participants who reported working 41-54 h per week and more than 55 h compared to those who worked 40 h or less over a time interval of 5 years. In a subsample of the population-based prospective Gutenberg Health Study (GHS) study, we examined working participants younger than 65 years at baseline (n = 7241) and after 5 years. To test the association of working time at baseline and incident cardiovascular events and diabetes type II, we estimated hazard ratios (HR) using competing risks models. For a change in the arterial stiffness index (SI) based on assessment using a Pulse Trace PCA2 device, we used multivariate linear regression models. The SI increased in those working more than 55 h per week (beta coefficiant = 0.32 m/s (95% CI 0.07-0.58) compared to those working 40 h and less after adjustment for sex, age and SES. Due to small numbers there was no significant association of working hours and clinically manifest cardiovascular events and diabetes type II in the 5-year follow-up time. Further studies are needed to confirm the results on working hours and arterial stiffness. Analyses of the 10-year follow-up with more events may clarify the results for incident cardiovascular events and metabolic outcomes.
Identifiants
pubmed: 34767077
doi: 10.1007/s00420-021-01786-9
pii: 10.1007/s00420-021-01786-9
pmc: PMC8755657
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
303-312Subventions
Organisme : BMBF
ID : 01EO1503
Informations de copyright
© 2021. The Author(s).
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