A lymphocyte-glia connection sets the pace for smoldering inflammation.

Central Nervous System Humans Inflammation Lymphocytes Multiple Sclerosis Neuroglia

Journal

Cell
ISSN: 1097-4172
Titre abrégé: Cell
Pays: United States
ID NLM: 0413066

Informations de publication

Date de publication:
11 11 2021
Historique:
received: 11 10 2021
revised: 14 10 2021
accepted: 15 10 2021
entrez: 12 11 2021
pubmed: 13 11 2021
medline: 25 12 2021
Statut: ppublish

Résumé

Successful therapeutic options directly targeting disability progression in patients with multiple sclerosis (MS), a chronic inflammatory disorder of the central nervous system, are lacking. Now, a study published in Nature by Absinta and colleagues profiles a lymphocyte-glia connection at the edge of chronic active lesions that continuously drives neurodegenerative pathways.

Identifiants

DOI: 10.1016/j.cell.2021.10.018 PMID: 34767775
pubmed: 34767775
pii: S0092-8674(21)01234-4
doi: 10.1016/j.cell.2021.10.018
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

5696-5698

Commentaires et corrections

Type : CommentOn

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Auteurs

Stefan Bittner (S)

Department of Neurology, Focus Program Translational Neuroscience (FTN) and Immunotherapy (FZI), Rhine-Main Neuroscience Network (rmn2), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.

Frauke Zipp (F)

Department of Neurology, Focus Program Translational Neuroscience (FTN) and Immunotherapy (FZI), Rhine-Main Neuroscience Network (rmn2), University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany. Electronic address: zipp@uni-mainz.de.

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Classifications MeSH

questionsmedicales.fr › Système nerveux › Système nerveux central › A lymphocyte-glia connection sets the pace for...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › A lymphocyte-glia connection sets the pace for...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Inflammation › A lymphocyte-glia connection sets the pace for...
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › A lymphocyte-glia connection sets the pace for...
questionsmedicales.fr › Maladies du système immunitaire › Maladies auto-immunes › Maladies auto-immunes du système nerveux › Maladies démyélinisantes auto-immunes du SNC › Sclérose en plaques › A lymphocyte-glia connection sets the pace for...
questionsmedicales.fr › Cellules › Névroglie › A lymphocyte-glia connection sets the pace for...