Atypical microbial keratitis.

Achromobacter Achromobacter xylosoxidans Atypical keratitis Atypical mycobacteria Cornea Infections Infectious crystalline keratopathy Infectious keratitis Infective keratitis Keratitis LASIK Microbial keratitis Nocardia Pythium Refractive surgery

Journal

The ocular surface
ISSN: 1937-5913
Titre abrégé: Ocul Surf
Pays: United States
ID NLM: 101156063

Informations de publication

Date de publication:
04 2023
Historique:
received: 06 09 2021
revised: 29 10 2021
accepted: 01 11 2021
medline: 14 8 2023
pubmed: 13 11 2021
entrez: 12 11 2021
Statut: ppublish

Résumé

Atypical microbial keratitis refers to corneal infections caused by micro-organisms not commonly encountered in clinical practice. Unlike infections caused by common bacteria, cases of atypical microbial keratitis are often associated with worse clinical outcomes and visual prognosis. This is due to the challenges in the identification of causative organisms with standard diagnostic techniques, resulting in delays in the initiation of appropriate therapies. Furthermore, due to the comparatively lower incidence of atypical microbial keratitis, there is limited literature on effective management strategies for some of these difficult to manage corneal infections. This review highlights the current management and available evidence of atypical microbial keratitis, focusing on atypical mycobacteria keratitis, nocardia keratitis, achromobacter keratitis, and pythium keratitis. It will also describe the management of two uncommonly encountered conditions, infectious crystalline keratopathy and post-refractive infectious keratitis. This review can be used as a guide for clinicians managing patients with such challenging corneal infections.

Identifiants

pubmed: 34768003
pii: S1542-0124(21)00128-2
doi: 10.1016/j.jtos.2021.11.001
pii:
doi:

Types de publication

Review Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

424-439

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest All authors have no conflicts of interest to declare.

Auteurs

Hon Shing Ong (HS)

Corneal and External Diseases Department, Singapore National Eye Centre, Singapore; Tissue Engineering and Cell Therapy Department, Singapore Eye Research Institute, Singapore; Department of Ophthalmology and Visual Science, Duke-National University of Singapore (NUS) Graduate Medical School, Singapore. Electronic address: honshing@gmail.com.

Namrata Sharma (N)

Department of Ophthalmology, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Lynette M Phee (LM)

Department of Pathology, Sengkang General Hospital, SingHealth, Singapore.

Jodhbir S Mehta (JS)

Corneal and External Diseases Department, Singapore National Eye Centre, Singapore; Tissue Engineering and Cell Therapy Department, Singapore Eye Research Institute, Singapore; Department of Ophthalmology and Visual Science, Duke-National University of Singapore (NUS) Graduate Medical School, Singapore; School of Material Science & Engineering and School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore. Electronic address: jodmehta@gmail.com.

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Classifications MeSH