Impact of Rhythm vs. Rate Control in Atrial Fibrillation on the Long-Term Outcome of Patients Undergoing Transcatheter Edge-to-Edge Mitral Valve Repair.
MitraClip
elderly
heart failure
mitral regurgitation
pharmacological rhythm control
rate-control
rhythm-control
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
28 Oct 2021
28 Oct 2021
Historique:
received:
15
09
2021
revised:
20
10
2021
accepted:
28
10
2021
entrez:
13
11
2021
pubmed:
14
11
2021
medline:
14
11
2021
Statut:
epublish
Résumé
Atrial fibrillation (AF) is a highly prevalent comorbidity in patients with severe mitral valve regurgitation (MR) undergoing transcatheter mitral valve repair (TMVR) and has been shown to significantly worsen their outcome. However, data on the impact of AF treatment strategy in this rapidly growing cohort of patients is unknown. In a multicenter, observational cohort study, 542 consecutive patients undergoing TMVR were enrolled, and subsequently, comprehensive survival analyses according to AF status and therapy were performed using propensity score matching and Cox regression. In the analyzed cohort, 373 (73.3%) of the TMVR patients had concomitant AF. Of these patients, 212 (59%) were on rate control therapy and 161 (41%) were on rhythm control therapy. At 3 years, significantly reduced cumulative survival was observed for patients on rhythm compared to patients on rate control (46.7% (75/161) vs. 56.5% (91/161),
Identifiants
pubmed: 34768567
pii: jcm10215044
doi: 10.3390/jcm10215044
pmc: PMC8584691
pii:
doi:
Types de publication
Journal Article
Langues
eng
Références
Am J Med. 2013 Oct;126(10):887-93
pubmed: 24054956
N Engl J Med. 2018 Dec 13;379(24):2307-2318
pubmed: 30280640
J Interv Cardiol. 2020 Aug 28;2020:6542028
pubmed: 32934608
J Am Coll Cardiol. 2019 Jan 29;73(3):264-274
pubmed: 30678755
N Engl J Med. 1991 Mar 21;324(12):781-8
pubmed: 1900101
Lancet. 2016 Mar 26;387(10025):1324-34
pubmed: 27025438
N Engl J Med. 2002 Dec 5;347(23):1825-33
pubmed: 12466506
Heart Fail Rev. 2021 May;26(3):531-543
pubmed: 33169339
Catheter Cardiovasc Interv. 2017 Nov 15;90(6):1038-1045
pubmed: 28568427
J Thorac Cardiovasc Surg. 2017 Jun;153(6):1330-1354.e1
pubmed: 28390766
Ann Thorac Surg. 2017 Jan;103(1):329-341
pubmed: 28007240
Biomolecules. 2018 Nov 19;8(4):
pubmed: 30463247
JACC Cardiovasc Interv. 2019 Mar 25;12(6):569-578
pubmed: 30898255
Eur Heart J. 2021 Oct 21;42(40):4194
pubmed: 34520521
J Cardiovasc Electrophysiol. 2020 May;31(5):1040-1047
pubmed: 32115777
Eur Heart J. 2020 Aug 7;41(30):2863-2873
pubmed: 31298266
N Engl J Med. 2011 Apr 14;364(15):1395-406
pubmed: 21463154
J Interv Card Electrophysiol. 2022 Jan;63(1):207-214
pubmed: 33634337
Catheter Cardiovasc Interv. 2021 May 1;97(6):1252-1256
pubmed: 33016645
N Engl J Med. 2008 Jun 19;358(25):2667-77
pubmed: 18565859
J Interv Card Electrophysiol. 2021 Sep;61(3):609-615
pubmed: 32888121
Medicine (Baltimore). 2020 Oct 2;99(40):e22195
pubmed: 33019394
Drugs Aging. 2020 Nov;37(11):839-844
pubmed: 32936416
N Engl J Med. 2018 Feb 01;378(5):417-427
pubmed: 29385358
Am J Cardiol. 2017 Dec 1;120(11):2035-2040
pubmed: 29033048
J Cardiovasc Electrophysiol. 2021 Oct;32(10):2873-2878
pubmed: 33783900