Risk Factors for Lead-Related Venous Obstruction: A Study of 2909 Candidates for Lead Extraction.

abandoned lead lead-related venous obstruction risk factors for venous obstruction transvenous lead extraction

Journal

Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588

Informations de publication

Date de publication:
03 Nov 2021
Historique:
received: 15 09 2021
revised: 10 10 2021
accepted: 02 11 2021
entrez: 13 11 2021
pubmed: 14 11 2021
medline: 14 11 2021
Statut: epublish

Résumé

our knowledge of lead-related venous stenosis/occlusion (LRVSO) remains limited and there is still controversy regarding the risk factors for LRVSO. Venography is mandatory before transvenous lead extraction (TLE). we performed a retrospective analysis of venograms in 2909 patients (39.43% females, average age 66.90 years) who underwent TLE between 2008 and 2021 at high-volume centers. the severity of LRVSO was likely to be dependent on the number of leads in the system (OR = 1.345; the severity of LRVSO is probably dependent on the mechanical impact of the implanted/abandoned leads on the vein wall, therefore the study has demonstrated the central role of system-/procedure-related risk factors. The thrombotic mechanism may be less important, especially long after implantation, and for this reason the combined prediction model for LRVSO in this study was more effective than the CHA2DS2-VASc score.

Sections du résumé

BACKGROUND BACKGROUND
our knowledge of lead-related venous stenosis/occlusion (LRVSO) remains limited and there is still controversy regarding the risk factors for LRVSO. Venography is mandatory before transvenous lead extraction (TLE).
METHODS METHODS
we performed a retrospective analysis of venograms in 2909 patients (39.43% females, average age 66.90 years) who underwent TLE between 2008 and 2021 at high-volume centers.
RESULTS RESULTS
the severity of LRVSO was likely to be dependent on the number of leads in the system (OR = 1.345;
CONCLUSIONS CONCLUSIONS
the severity of LRVSO is probably dependent on the mechanical impact of the implanted/abandoned leads on the vein wall, therefore the study has demonstrated the central role of system-/procedure-related risk factors. The thrombotic mechanism may be less important, especially long after implantation, and for this reason the combined prediction model for LRVSO in this study was more effective than the CHA2DS2-VASc score.

Identifiants

pubmed: 34768676
pii: jcm10215158
doi: 10.3390/jcm10215158
pmc: PMC8584439
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Marek Czajkowski (M)

Department of Cardiac Surgery, Medical University of Lublin, 20-090 Lublin, Poland.

Wojciech Jacheć (W)

2nd Department of Cardiology, Faculty of Medical Science in Zabrze, Medical University of Silesia in Katowice, 41-800 Zabrze, Poland.

Anna Polewczyk (A)

Department of Physiology, Patophysiology and Clinical Immunology, Collegium Medicum of Jan Kochanowski University, 25-317 Kielce, Poland.
Department of Cardiac Surgery, Świętokrzyskie Center of Cardiology, 25-736 Kielce, Poland.

Jarosław Kosior (J)

Department of Cardiology, Masovian Specialistic Hospital of Radom, 26-617 Radom, Poland.

Dorota Nowosielecka (D)

Department of Cardiology, The Pope John Paul II Province Hospital of Zamość, 22-400 Zamość, Poland.

Łukasz Tułecki (Ł)

Department of Cardiac Surgery, The Pope John Paul II Province Hospital of Zamość, 22-400 Zamość, Poland.

Paweł Stefańczyk (P)

Department of Cardiology, The Pope John Paul II Province Hospital of Zamość, 22-400 Zamość, Poland.

Andrzej Kutarski (A)

Department of Cardiology, Medical University of Lublin, 20-090 Lublin, Poland.

Classifications MeSH